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2′-Deoxyinosine

SIGMA/D5287 - ≥98%

Synonym: 9-(2-Deoxy-β-D-ribofuranosyl)hypoxanthine

CAS Number: 890-38-0
Empirical Formula (Hill Notation): C10H12N4O4
Molecular Weight: 252.23
EC Number: 212-964-1
MDL Number: MFCD00005762
Linear Formula: C10H12N4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D5287-100MG 100 mg
 $55.20
1/EA		 Add To Favorites
45-D5287-1G 1 g
 $263.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D5287-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D5287-1G

 

assay ≥98%
biological source synthetic (organic)
form powder
impurities inosine, essentially free
InChI 1S/C10H12N4O4/c15-2-6-5(16)1-7(18-6)14-4-13-8-9(14)11-3-12-10(8)17/h3-7,15-16H,1-2H2,(H,11,12,17)/t5-,6+,7+/m0/s1
InChI key VGONTNSXDCQUGY-RRKCRQDMSA-N
Quality Level 200 
SMILES string OC[C@H]1O[C@H](C[C@@H]1O)n2cnc3C(=O)NC=Nc23
solubility 1 M NH4OH: 50 mg/mL, clear, colorless
storage temp. −20°C
Application: 2′-Deoxyinosine has been used in the quantification of nucleoside forms of DNA lesion in a single DNA sample by liquid chromatography tandem mass spectrometry (LC-MS/MS). It has also been used as a standard for high performance liquid chromatography analysis.
Biochem/physiol Actions: 2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. 2′-Deoxyinosine in DNA can arise from deamination of adenosine. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability.
Biochem/physiol Actions: 2′-Deoxyinosine is a nucleoside form of hypoxanthine. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinosine is formed from nitrosative deamination by N2O3.
Packaging: 1 g in poly bottle
Packaging: 100 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98%
Storage Temp. −20°C
UNSPSC 41106305

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