Synonym: ASTA C 4898; Cormelian; N,N′-bis(3-[3,4,5-Trimethoxybenzoyloxy]propyl)homopiperazine dihydrochloride
CAS Number: 20153-98-4
Empirical Formula (Hill Notation): C31H44N2O10 · 2HCl
Molecular Weight: 677.61
EC Number: 243-548-8
MDL Number: MFCD00133267
Linear Formula: C31H44N2O10 · 2HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D5294-100MG
| color |
white |
| form |
powder |
| InChI |
1S/C31H44N2O10.2ClH/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4;;/h18-21H,7-17H2,1-6H3;2*1H |
| InChI key |
VILIWRRWAWKXRW-UHFFFAOYSA-N |
| Quality Level |
200  |
| SMILES string |
Cl[H].Cl[H].COc1cc(cc(OC)c1OC)C(=O)OCCCN2CCCN(CCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2 |
| solubility |
H2O: 10 mg/mL |
| storage temp. |
2-8°C |
| Application: |
Dilazep dihydrochloride has been used in estrogen receptor (ERα) antagonistic assay. It has also been used as an equilibrative nucleoside transporter inhibitor (ENT 1 and 2) in cancer cell lines. |
| Biochem/physiol Actions: |
Dilazep is a equilibrative nucleoside transporter 1 (ENTs) inhibitor. It is an antianginal drug and an effective coronary vasodilator. Dilazep elicits anti-albuminuric effects and is an anti-platelet agent. It is a potent adenosine uptake inhibitor and suppresses effects of ischemia. |
| General description: |
Dilazep comprises central cyclic diamine and phenyl rings connected via alkyl linkers. |
| Packaging: |
100 mg in glass bottle |
| Packaging: |
50 mg in poly bottle |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |