2′-Deoxyuridine
SIGMA/D5412 - ≥98.5%
Synonym: 1-(2-Deoxy-β-D-ribofuranosyl)uracil; Uracil deoxyriboside
CAS Number: 951-78-0
Empirical Formula (Hill Notation): C9H12N2O5
Molecular Weight: 228.20
EC Number: 213-455-7
MDL Number: MFCD00006527
Linear Formula: C9H12N2O5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D5412-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D5412-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D5412-250MG
| assay | ≥98.5% |
| biological source | synthetic (organic) |
| form | powder |
| impurities | Thymidine, free |
| InChI | 1S/C9H12N2O5/c12-4-6-5(13 |
| InChI key | MXHRCPNRJAMMIM-SHYZEUOFSA |
| Quality Level | 300  |
| SMILES string | OC[C@H]1O[C@H](C[C@@H]1O) |
| solubility | water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow |
| Application: | 2′-Deoxyuridine has been used as a: • precursor of [3H]thymidine triphosphate (TTP) in place of thymidine to avoid a potential thymidine block in relative proliferation assays • nucleoside supplement for cell cycle synchronization and DNA replication inhibition • mitotic inhibitor in culture media to minimize the proliferation of glial cells |
| Biochem/physiol Actions: | 2′-Deoxyuridine (dU) is frequently halogenated to create thymidine analogs useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2′-deoxyuridines used as labeling substrates include chloro-2′-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogs of 2′-deoxyuridine include 5-ethynyl-2′-deoxyuridine (DdU) and 5-hydroxymethyl-2′-deoxyuridine (HmdU). |
| Packaging: | 1, 5 g in poly bottle |
| Packaging: | 100, 250 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.5% |
| UNSPSC | 41106305 |