Synonym: 5β,20(22)-Cardenolide-3β,14-diol-3-(O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-O-2,6-dideoxy-β-D-ribo-hexopyranosyl-[1→4]-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy; Digitoxoside; Lanatoxin
CAS Number: 71-63-6
Empirical Formula (Hill Notation): C41H64O13
Molecular Weight: 764.94
EC Number: 200-760-5
MDL Number: MFCD00003686
Linear Formula: C41H64O13
Product Type: Chemical
| assay |
≥92% (HPLC) |
| form |
powder |
| InChI |
1S/C41H64O13/c1-20-36(46)29(42)16-34(49-20)53-38-22(3)51-35(18-31(38)44)54-37-21(2)50-33(17-30(37)43)52-25-8-11-39(4)24(15-25)6-7-28-27(39)9-12-40(5)26(10-13-41(28,40)47)23-14-32(45)48-19-23/h14,20-22,24-31,33-38,42-44,46-47H,6-13,15-19H2,1-5H3/t20-,21-,22-,24-,25+,26-,27+,28-,29+,30+,31+,33+,34+,35+,36-,37-,38-,39+,40-,41+/m1/s1 |
| InChI key |
WDJUZGPOPHTGOT-XUDUSOBPSA-N |
| mp |
240 °C (dec.) (lit.) |
| Quality Level |
200  |
| SMILES string |
[H][C@@]1(C[C@H](O)[C@H](O[C@@]2([H])C[C@H](O)[C@H](O[C@@]3([H])C[C@H](O)[C@H](O)[C@@H](C)O3)[C@@H](C)O2)[C@@H](C)O1)O[C@H]4CC[C@@]5(C)[C@]([H])(CC[C@]6([H])[C@]5([H])CC[C@]7(C)[C@]([H])(CC[C@]67O)C8=CC(=O)OC8)C4 |
| solubility |
chloroform: soluble |
| Application: |
Digitoxin has been used as a labeled drugs for binding sites on human serum albumin (HSA). It has also been used to test its anti-transmissible gastroenteritis virus (TGEV) activity. |
| General description: |
Digitoxin is a cardiac glycoside (CG). It is a cardiotonic drug, which exhibits cardiac and anti-cancer properties. Digitoxin inhibits nuclear factor kappa B (NF-κB) signaling. It is used to treat congestive heart failure and cardiac arrhythmia. Digitoxin prevents microtubule formation. |
| Packaging: |
1, 5, 10 g in glass bottle |
| Packaging: |
250, 500 mg in glass bottle |
| Purity |
≥92% (HPLC) |
| mp |
240 °C (dec.) (lit.) |
| UNSPSC |
12161501 |
GHS06,GHS08