3′,4′-Dimethoxyflavone
SIGMA/D6571
Synonym: 2-
CAS Number: 4143-62-8
Empirical Formula (Hill Notation): C17H14O4
Molecular Weight: 282.29
MDL Number: MFCD00143009
Linear Formula: C17H14O4
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C17H14O4/c1-19-15-8-7- |
| InChI key | ZGHORMOOTZTQFL-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | COc1ccc(cc1OC)C2=CC(=O)c3 |
| solubility | DMSO: ≥20 mg/mL |
| storage temp. | room temp |
| Application: | 3′,4′-Dimethoxyflavone has been used in urease inhibition assay. |
| Biochem/physiol Actions: | 3′,4′-dimethoxyflavone is a competitive antagonist of the AhR that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines. The compound blocks transformation of the cytosolic AhR complex, and formation of nuclear AhR complexes. |
| Biochem/physiol Actions: | 3′,4′-dimethoxyflavone is a competitive antagonist of the aryl hydrocarbon receptor (AhR) that inhibits AhR-mediated induction of CYP1A1, and also displays antiestrogen activity in breast tumor cell lines. |
| Biochem/physiol Actions: | 3′,4′-Dimethoxyflavone is a flavone compound, which has the ability to prevent the production and accumulation of poly (ADP-ribose) (PAR) polymer. It guards against N-methyl- |
| Packaging: | 5, 25 mg in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352200 |