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(R)-DRF053 hydrochloride hydrate

SIGMA/D6946 - ≥98% (HPLC)

Synonym: 2-[[9-(1-Methylethyl)-6-[[3-(2-pyridinyl)phenyl]amino]- 9H-purin-2-yl]amino]-1-butanol hydrochloride hydrate

Empirical Formula (Hill Notation): C23H27N7O · xHCl · yH2O
Molecular Weight: 417.51 (anhydrous free base basis)
MDL Number: MFCD17215921
Linear Formula: C23H27N7O · xHCl · yH2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D6946-5MG 5 mg
 $111.00
1/EA		 Add To Favorites
45-D6946-25MG 25 mg
 $451.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color yellow
form powder
InChI 1S/C23H27N7O.ClH.H2O/c1-4-17(13-31)27-23-28-21(20-22(29-23)30(14-25-20)15(2)3)26-18-9-7-8-16(12-18)19-10-5-6-11-24-19;;/h5-12,14-15,17,31H,4,13H2,1-3H3,(H2,26,27,28,29);1H;1H2/t17-;;/m1../s1
InChI key ZOSNTFVWVJFXQO-ZEECNFPPSA-N
Quality Level 100 
SMILES string O.Cl.CC[C@H](CO)Nc1nc(Nc2cccc(c2)-c3ccccn3)c4ncn(C(C)C)c4n1
solubility DMSO: ≥30 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: DRF053 is a more potent version of roscovitine.
Biochem/physiol Actions: DRF053 is a more potent version of roscovitine. It is 2 fold more potent against CDK5 (80 nM) and over 150 times more potent against CDK1 (14 nM).
Features and Benefits: This compound is featured on the CDKs  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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