Synonym: 11-Deoxycorticosterone acetate; 21-Acetoxy-4-pregnene-3,20-dione; 21-Acetoxyprogesterone; 21-Hydroxy-4-pregnene-3,20-dione 21-acetate; 21-Hydroxyprogesterone 21-acetate; 4-Pregnen-21-ol-3,20-dione 21-acetate; Cortexone acetate; DOC acetate
CAS Number: 56-47-3
Empirical Formula (Hill Notation): C23H32O4
Molecular Weight: 372.50
EC Number: 200-275-9
MDL Number: MFCD00003660
Linear Formula: C23H32O4
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7000-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7000-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7000-5G
| assay |
≥98% (HPLC) |
| biological source |
synthetic (organic) |
| form |
powder |
| InChI |
1S/C23H32O4/c1-14(24)27-13-21(26)20-7-6-18-17-5-4-15-12-16(25)8-10-22(15,2)19(17)9-11-23(18,20)3/h12,17-20H,4-11,13H2,1-3H3/t17-,18-,19-,20+,22-,23-/m0/s1 |
| InChI key |
VPGRYOFKCNULNK-ACXQXYJUSA-N |
| Quality Level |
200  |
| shipped in |
ambient |
| SMILES string |
[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@]([H])(CC[C@@]24[H])C(=O)COC(C)=O |
| solubility |
acetone: soluble (1 in 30) |
| |
alcohol: soluble (1 in 50) |
| |
chloroform: freely soluble |
| |
dioxane: slightly soluble |
| |
H2O: insoluble |
| |
vegetable oils: slightly soluble |
| sterility |
non-sterile |
| storage temp. |
room temp |
| Application: |
Deoxycorticosterone acetate has been used to induce hypertensive pregnancy. It has also been used to investigate the effect of low epicatechin dosing on the cardiovascular function of deoxycorticosterone acetate (DOCA)-salt hypertensive rats. |
| General description: |
Deoxycorticosterone acetate is an endogenous neurosteroid found in brain and peripheral circulation, which is produced by progesterone. It is both a mineralocorticoid and a glucocorticoid. It is used to treat adrenocortical insufficiency or Addison′s disease. Deoxycorticosterone acetate improves insulin sensitivity. It acts as a precursor to glucocorticoid corticosterone and the GABAergic neuroactive steroid (3α,5α)-3,21-dihydroxypregnan-20-one. |
| Packaging: |
1, 5, 25 g in poly bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |