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Dapoxetine hydrochloride

SIGMA/D7071 - ≥98% (HPLC)

Synonym: (S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride; S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride, LY-210448 hydrochloride

CAS Number: 129938-20-1
Empirical Formula (Hill Notation): C21H23NO · HCl
Molecular Weight: 341.87
MDL Number: MFCD08272809
Linear Formula: C21H23NO · HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-D7071-10MG 10 mg
$121.00
1/EA
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45-D7071-50MG 50 mg
$475.00
1/EA
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assay ≥98% (HPLC)
color white
form powder
InChI 1S/C21H23NO.ClH/c1-22(2)20(18-10-4-3-5-11-18)15-16-23-21-14-8-12-17-9-6-7-13-19(17)21;/h3-14,20H,15-16H2,1-2H3;1H/t20-;/m0./s1
InChI key IHWDIQRWYNMKFM-BDQAORGHSA-N
optical activity [α]/D +125 to +135°, c = 1 in methanol
originator Eli Lilly
Quality Level 100 
SMILES string Cl.CN(C)[C@@H](CCOc1cccc2ccccc12)c3ccccc3
solubility DMSO: ≥20 mg/mL
storage condition desiccated
storage temp. room temp
Biochem/physiol Actions: Dapoxetine is capable of blocking recombinant Kv4.3 potassium voltage-gated channels. It is considered as safe.
Biochem/physiol Actions: Potent and selective SSRI
Biochem/physiol Actions: Potent Selective serotonin reuptake inhibitor (SSRI); used in treatment of premature ejaculation
Features and Benefits: This compound is featured on the Biogenic Amine Transporters  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Eli Lilly . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Dapoxetine ((+)-(S)-N,N-dimethyl-(α)-[2(1naphthal enyloxy)ethyl]-benzenemethanamine hydrochloride) possess a similar structure as that of fluoxetine.
Packaging: 10, 50 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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