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2′-Deoxyguanosine monohydrate

SIGMA/D7145 - 99-100%

Synonym: 2′-Deoxyguanosine hydrate; 9-(2-Deoxy-β-D-ribofuranosyl)guanine; Guanine-2′-deoxyriboside

CAS Number: 312693-72-4
Empirical Formula (Hill Notation): C10H13N5O4 · H2O
Molecular Weight: 285.26
MDL Number: MFCD00150760
Linear Formula: C10H13N5O4 · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D7145-25MG 25 mg
 $47.90
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45-D7145-100MG 100 mg
 $111.00
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45-D7145-1G 1 g
 $394.00
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45-D7145-5G 5 g
 $1310.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7145-25MG.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7145-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7145-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7145-5G

 

assay 99-100%
biological source synthetic (organic)
form powder
InChI 1S/C10H13N5O4.H2O/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6;/h3-6,16-17H,1-2H2,(H3,11,13,14,18);1H2/t4-,5+,6+;/m0./s1
InChI key LZSCQUCOIRGCEJ-FPKZOZHISA-N
Quality Level 200 
SMILES string O.NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](CO)O3)C(=O)N1
solubility 1 M NH4OH: 50 mg/mL, clear, colorless
Application: 2′-Deoxyguanosine monohydrate has been used as a nucleoside supplement:
• to study its effect on mitochondrial DNA copy number in deoxyguanosine kinase (dguok) mutant zebrafish,
• in tissue culture medium for deoxyribonucleotide triphosphate (dNTP) synthesis,
• in RPMI (Roswell Park Memorial Institute)-1640 medium to eliminate the endogenous thymocytes
Biochem/physiol Actions: Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphorylation (kinases) forms deoxyguanosine triphosphate (dGTP) which is used by DNA polymerases and reverse transcriptases to synthesize DNA(s). Deoxyguanosine is the most electron-rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.
Packaging: 1, 5 g in poly bottle
Packaging: 25, 100 mg in poly bottle
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity 99-100%
UNSPSC 41106305

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