Diosmetin

SIGMA/D7321

Synonym: 3′,5,7-Trihydroxy-4′-methoxyflavone; 4′-Methylluteolin; 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromen-4-one; Luteolin 4′-methyl ether

CAS Number: 520-34-3
Empirical Formula (Hill Notation): C₁₆H₁₂O₆
Molecular Weight: 300.26
EC Number: 208-291-8
MDL Number: MFCD00017425
Linear Formula: C₁₆H₁₂O₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-D7321-10MG	10 mg	$0.00 1/EA CALL FOR PRICE	Add To Favorites
45-D7321-100MG	100 mg	$309.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7321-10MG.

Properties
Descriptions
Safety Info.
Basic Data

application(s)	metabolomics vitamins, nutraceuticals, and natural products
assay	≥98% (HPLC)
color	light yellow to yellow
form	powder
InChI	1S/C16H12O6/c1-21-13-3-2-8(4-10(13)18)14-7-12(20)16-11(19)5-9(17)6-15(16)22-14/h2-7,17-19H,1H3
InChI key	MBNGWHIJMBWFHU-UHFFFAOYSA-N
Quality Level	200
SMILES string	COc1ccc(cc1O)C2=CC(=O)c3c(O)cc(O)cc3O2
solubility	DMSO: 1 mg/mL, clear, faintly yellow to greenish-yellow
storage temp.	2-8°C

Application:	Diosmetin has been used to test its protective effects on chronic stress memory and cognitive impairment in mice model.
Biochem/physiol Actions:	Diosmetin exhibits anti-inflammatory, anti-cancer, antimicrobial, phytoestrogenic, and neuroprotective properties. It displays cytoprotective effects against lipopolysaccharide (LPS)-induced acute lung injury (ALI) by inhibiting nucleotide-binding domain (NOD)-like receptor protein 3 (NLRP3) inflammasome and activating nuclear factor erythroid 2–related factor 2 (Nrf2).
Biochem/physiol Actions:	Flavonoid from Citrus limon. Antioxidant. Inhibits carcinogen activation by inhibiting the CYP1A1 enzyme.
General description:	Diosmetin is a methylated aglycone flavone of diosmin. It is present abundantly in citrus fruits, Olea europaea L. (olive tree) leaves, and in the legume of Acacia farnesiana tree.
Packaging:	10 mg in glass insert
Packaging:	100, 500 mg in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H302
Hazard Codes	Xn
Risk Statements	22
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352205

To Order From a Quote