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Diethylumbelliferyl phosphate

SIGMA/D7692 - ≥98% (HPLC), oil

Synonym: DEUP; UBP

CAS Number: 897-83-6
Empirical Formula (Hill Notation): C14H17O6P
Molecular Weight: 312.25
Linear Formula: C14H17O6P
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D7692-5MG 5 mg
 $184.00
1/EA		 Add To Favorites
45-D7692-25MG 25 mg
 $711.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color colorless to yellow
form oil
InChI 1S/C14H17O6P/c1-4-17-21(16,18-5-2)20-11-6-7-12-10(3)8-14(15)19-13(12)9-11/h6-9H,4-5H2,1-3H3
InChI key GHGRYKAFUNNHBG-UHFFFAOYSA-N
Quality Level 100 
SMILES string CCOP(=O)(OCC)Oc1ccc2C(C)=CC(=O)Oc2c1
solubility DMSO: >5 mg/mL
storage temp. −20°C
Application: Diethylumbelliferyl phosphate has been used as a lipase inhibitor to treat wild-type myeloblasts for in vitro neutrophil differentiation assays.
Biochem/physiol Actions: Diethylumbelliferyl phosphate (DEUP), an organophosphate does not block protein kinase activity A in vitro.
Biochem/physiol Actions: Diethylumbelliferyl phosphate is a selective, potent cholesterol esterase inhibitor. It blocks steroidogenesis primarily by preventing cholesterol transport into the mitochondria of steroidogenic cells. Inhibitors of cholesterol esterase are anticipated to limit the absorption of dietary cholesterol. IC50 = 11.6 μM.
Packaging: 5, 25 mg in glass bottle
Symbol GHS06  GHS06
Signal word Danger
Hazard statements H300
Precautionary statements P264 - P301 + P310
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR UN 2811 6.1 / PGII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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