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Demethoxycurcumin

SIGMA/D7696 - ≥98% (HPLC)

Synonym: (E,E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione; Curcumin II; Desmethoxycurcumin; Monodemethoxycurcumin

CAS Number: 22608-11-3
Empirical Formula (Hill Notation): C20H18O5
Molecular Weight: 338.35
MDL Number: MFCD03427310
Linear Formula: C20H18O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D7696-5MG 5 mg
 $195.00
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45-D7696-25MG 25 mg
 $749.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts D7696-25MG

 

assay ≥98% (HPLC)
color orange
form powder
InChI 1S/C20H18O5/c1-25-20-12-15(6-11-19(20)24)5-10-18(23)13-17(22)9-4-14-2-7-16(21)8-3-14/h2-12,21,24H,13H2,1H3/b9-4+,10-5+
InChI key HJTVQHVGMGKONQ-LUZURFALSA-N
Quality Level 100 
SMILES string COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)cc2)ccc1O
solubility DMSO: ≥10 mg/mL
storage condition protect from light
storage temp. 2-8°C
Biochem/physiol Actions: Demethoxycurcumin (DMC) is a derivative or curcumin, and represents one of the major active components of curcumin products isolated from Curcumae sp. DMC inhibits LPS-induced nitric oxide (NO) production, and expression of iNOS and COX2 in RAW264.7 cells by blocking NF-kB activation. DMC also inhibits NF-kB dependent iNOS, TNFα and IL-1β expression in LPS-treated rat microglial cells. DMC suppresses expression of MMPs and ICAM-1 in MDA-MB-231 human breast cancer cells by inhibition of NF-kB.
Packaging: 5, 25 mg in glass bottle
Symbol GHS09  GHS09
Signal word Warning
Hazard statements H400
Precautionary statements P273
Hazard Codes N
Risk Statements 50
Safety Statements 61
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352205

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