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3,4-Dichloroisocoumarin

SIGMA/D7910 - serine protease inhibitor

Synonym: 3,4-DCI; 3,4-Dichloro-2-benzopyran-1-one

CAS Number: 51050-59-0
Empirical Formula (Hill Notation): C9H4Cl2O2
Molecular Weight: 215.03
MDL Number: MFCD00036960
Linear Formula: C9H4Cl2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D7910-5MG 5 mg
 $254.00
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45-D7910-10MG 10 mg
 $465.00
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45-D7910-25MG 25 mg
 $1010.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7910-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D7910-25MG

 

assay ≥98% (TLC)
form powder
InChI 1S/C9H4Cl2O2/c10-7-5-3-1-2-4-6(5)9(12)13-8(7)11/h1-4H
InChI key SUGXUUGGLDCZKB-UHFFFAOYSA-N
Quality Level 200 
SMILES string ClC1=C(Cl)c2ccccc2C(=O)O1
solubility ethyl acetate: 49.00-51.00 mg/mL, clear, colorless to faintly yellow
storage temp. 2-8°C
Application: Useful in a rapid staining method for identification of macrophages; counts by this method were confirmed by the more complex morphological criteria, by phagocytosis, and by the presence of Fc receptors.
General description: Serine protease inhibitor. Active towards a wide range of serine proteases including granzymes. Not active toward β-lactamases.
Other Notes: Effective concentration 5-100 μM.
Packaging: 5, 10, 25 mg in glass bottle
Preparation Note: Half-life = 20 min at pH 7.5.
Purity ≥98% (TLC)
Storage Temp. 2-8°C
UNSPSC 12352202

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