Advanced Search



9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α

SIGMA/D8174 - solution, 10 mg/mL in methyl acetate

Synonym: U-46619; U46619

CAS Number: 56985-40-1
Empirical Formula (Hill Notation): C21H34O4
Molecular Weight: 350.49
MDL Number: MFCD00135238
Linear Formula: C21H34O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D8174-1MG 1 mg
 $349.00
1/EA		 Add To Favorites
45-D8174-5MG 5 mg
 $1370.00
1/EA		 Add To Favorites

 

concentration 10 mg/mL in methyl acetate
form solution
InChI 1S/C21H34O4/c1-2-3-6-9-17(22)12-13-19-18(16-14-20(19)25-15-16)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16?,17-,18-,19+,20?/m0/s1
InChI key LQANGKSBLPMBTJ-REGKDVDGSA-N
Quality Level 200 
shipped in dry ice
SMILES string CCCCC[C@H](O)C=C[C@H]1C2CC(CO2)[C@@H]1CC=C/CCCC(O)=O
storage temp. −20°C
Application: 9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α has been used:
• to induce aortic smooth muscle (SM) contraction in mice deficient in myosin light chain 9 (Myl9) gene
• to induce contraction as part of vascular reactivity experiments using mice aorta
• as a thromboxane/prostaglandin agonist to study the effect of dithiothreitol (DTT) on mice arterial vessel viability
Biochem/physiol Actions: 9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α is a thromboxane A2 agonist. It is useful in in vitro experiments to induce shape change, aggregation, secretion, phosphoinositide hydrolysis, and protein phosphorylation in platelets. It also causes an elevation in the cytosolic Ca++ levels slightly affecting the cyclic adenosine monophosphate (cAMP) formation. It acts as a potent stimulator of vascular cell adhesion molecule-1 (VCAM-1), which mediates leukocyte adhesion to the endothelium.
Features and Benefits: This compound is featured on the Prostanoid Receptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: 9,11-Dideoxy-11α,9α-epoxymethanoprostaglandin F2α is an endoperoxide/thromboxane analog.
Storage Temp. −20°C
UNSPSC 12352211

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Tariffs & Effects on Pricing

Tariff note: As we navigate the current environment of tariff surcharges and mid-year manufacturer price increases, we want to keep you informed. While we have avoided making specific decisions thus far, we anticipate that we will be forced to implement a cost adjustment policy to offset the fees we have already been absorbing. We are committed to transparency and moderation in this process.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top