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2′-Deoxyadenosine monohydrate

SIGMA/D8668 - powder, BioReagent, suitable for cell culture

Synonym: 9-(2-Deoxy-β-D-ribofuranosyl)adenine; Adenine deoxyriboside

CAS Number: 16373-93-6
Empirical Formula (Hill Notation): C10H13N5O3 · H2O
Molecular Weight: 269.26
EC Number: 213-488-7
MDL Number: MFCD00005754
Linear Formula: C10H13N5O3 · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D8668-1G 1 g
 $92.50
1/EA		 Add To Favorites
45-D8668-5G 5 g
 $314.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D8668-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D8668-5G

 

assay ≥99% (HPLC)
biological source synthetic (organic)
form powder
InChI 1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
InChI key OLXZPDWKRNYJJZ-RRKCRQDMSA-N
product line BioReagent
Quality Level 200 
SMILES string [H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
solubility H2O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp. 2-8°C
technique(s) cell culture | mammalian: suitable
Application: 2′-Deoxyadenosine monohydrate has been used as a nucleotide precursor:
• To study the importance of homologous recombination at the interface between replication and mitosis
• To analyze deoxynucleoside-assisted transductions
• To study the effect of increased deoxycytidine on gemcitabine resistance in pancreatic cancer cells
Application: 2′-Deoxyadenosine monohydrate has been used for the preparation of deoxyribonucleoside stock solution for the anaerobic culture of Bacillus mojavensis strains including JF-2 and two Bacillus subtilis strains.
Biochem/physiol Actions: Excess 2′-deoxyadenosine gets converted to adenosine triphosphate (dATP), which inhibits ribonucleotide reductase.
Packaging: 1, 5 g in poly bottle
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352207

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