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DMH1

SIGMA/D8946 - ≥98% (HPLC)

Synonym: 4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline; 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline

CAS Number: 1206711-16-1
Empirical Formula (Hill Notation): C24H20N4O
Molecular Weight: 380.44
MDL Number: MFCD18384963
Linear Formula: C24H20N4O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-D8946-5MG 5 mg
$227.00
1/EA
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45-D8946-25MG 25 mg
$952.00
1/EA
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assay ≥98% (HPLC)
color light yellow to orange
form powder
InChI 1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3
InChI key JMIFGARJSWXZSH-UHFFFAOYSA-N
Quality Level 100 
SMILES string CC(C)OC(C=C1)=CC=C1C(C=N2)=CN3C2=C(C4=CC=NC5=C4C=CC=C5)C=N3
solubility DMSO: 5 mg/mL, clear (warmed)
storage condition desiccated
storage temp. 2-8°C
Application: DMH1 has been used for bone morphogenetic protein (BMP) inhibition.
Biochem/physiol Actions: DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor.
Biochem/physiol Actions: DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH1 is a dorsomorphin analogue that exclusively targets the BMP but not the VEGF pathway.
General description: DMH1 stimulates neurogenesis of human-induced pluripotent stem cells (hiPSCs) and suppresses the growth and metastasis of lung cancer. It blocks cellular autophagy responses.
Packaging: 5, 25 mg in glass bottle
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 51111800

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