Synonym: 4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline; 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline
CAS Number: 1206711-16-1
Empirical Formula (Hill Notation): C24H20N4O
Molecular Weight: 380.44
MDL Number: MFCD18384963
Linear Formula: C24H20N4O
Product Type: Chemical
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| assay |
≥98% (HPLC) |
| color |
light yellow to orange |
| form |
powder |
| InChI |
1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3 |
| InChI key |
JMIFGARJSWXZSH-UHFFFAOYSA-N |
| Quality Level |
100  |
| SMILES string |
CC(C)OC(C=C1)=CC=C1C(C=N2)=CN3C2=C(C4=CC=NC5=C4C=CC=C5)C=N3 |
| solubility |
DMSO: 5 mg/mL, clear (warmed) |
| storage condition |
desiccated |
| storage temp. |
2-8°C |
| Application: |
DMH1 has been used for bone morphogenetic protein (BMP) inhibition. |
| Biochem/physiol Actions: |
DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor. |
| Biochem/physiol Actions: |
DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH1 is a dorsomorphin analogue that exclusively targets the BMP but not the VEGF pathway. |
| General description: |
DMH1 stimulates neurogenesis of human-induced pluripotent stem cells (hiPSCs) and suppresses the growth and metastasis of lung cancer. It blocks cellular autophagy responses. |
| Packaging: |
5, 25 mg in glass bottle |
| Hazard Codes |
T |
| Risk Statements |
25 |
| Safety Statements |
45 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
51111800 |