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DMH1

SIGMA/D8946 - ≥98% (HPLC)

Synonym: 4-[6-(4-Isopropoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline; 4-[6-[4-(1-Methylethoxy)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline

CAS Number: 1206711-16-1
Empirical Formula (Hill Notation): C24H20N4O
Molecular Weight: 380.44
MDL Number: MFCD18384963
Linear Formula: C24H20N4O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-D8946-5MG 5 mg
$243.00
1/EA
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45-D8946-25MG 25 mg
$1020.00
1/EA
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This picture is provided solely for illustration purposes, it may have been created or edited with AI. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts D8946-5MG

 

assay ≥98% (HPLC)
color light yellow to orange
form powder
InChI 1S/C24H20N4O/c1-16(2)29-19-9-7-17(8-10-19)18-13-26-24-22(14-27-28(24)15-18)20-11-12-25-23-6-4-3-5-21(20)23/h3-16H,1-2H3
InChI key JMIFGARJSWXZSH-UHFFFAOYSA-N
Quality Level 100 
SMILES string CC(C)OC(C=C1)=CC=C1C(C=N2)=CN3C2=C(C4=CC=NC5=C4C=CC=C5)C=N3
solubility DMSO: 5 mg/mL, clear (warmed)
storage condition desiccated
storage temp. 2-8°C
Application: DMH1 has been used for bone morphogenetic protein (BMP) inhibition.
Biochem/physiol Actions: DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor.
Biochem/physiol Actions: DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH1 is a dorsomorphin analogue that exclusively targets the BMP but not the VEGF pathway.
General description: DMH1 stimulates neurogenesis of human-induced pluripotent stem cells (hiPSCs) and suppresses the growth and metastasis of lung cancer. It blocks cellular autophagy responses.
Packaging: 5, 25 mg in glass bottle
Hazard Codes T
Risk Statements 25
Safety Statements 45
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 51111800

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