DMH1
SIGMA/D8946 - ≥98% (HPLC)
Synonym: 4-
CAS Number: 1206711-16-1
Empirical Formula (Hill Notation): C24H20N4O
Molecular Weight: 380.44
MDL Number: MFCD18384963
Linear Formula: C24H20N4O
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | light yellow to orange |
| form | powder |
| InChI | 1S/C24H20N4O/c1-16(2)29-1 |
| InChI key | JMIFGARJSWXZSH-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | CC(C)OC(C=C1)=CC=C1C(C=N2 |
| solubility | DMSO: 5 mg/mL, clear (warmed) |
| storage condition | desiccated |
| storage temp. | 2-8°C |
| Application: | DMH1 has been used for bone morphogenetic protein (BMP) inhibition. |
| Biochem/physiol Actions: | DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor. |
| Biochem/physiol Actions: | DMH1 is a highly selective Bone morphogenetic protein (BMP) inhibitor. DMH1 is a dorsomorphin analogue that exclusively targets the BMP but not the VEGF pathway. |
| General description: | DMH1 stimulates neurogenesis of human-induced pluripotent stem cells (hiPSCs) and suppresses the growth and metastasis of lung cancer. It blocks cellular autophagy responses. |
| Packaging: | 5, 25 mg in glass bottle |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 51111800 |

