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N-Desmethyltamoxifen HCl

SIGMA/D9069 - ≥98% (HPLC), solid

Synonym: (Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine; ICI 55,548

CAS Number: 15917-65-4
Empirical Formula (Hill Notation): C25H27NO·HCl
Molecular Weight: 393.95
MDL Number: MFCD03423594
Linear Formula: C25H27NO·HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-D9069-5MG 5 mg
$324.00
1/EA
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assay ≥98% (HPLC)
form solid
InChI 1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;
InChI key GMLHJWZEYLTNJW-BJFQDICYSA-N
Quality Level 100 
shipped in ambient
SMILES string Cl.CCC(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3
solubility DMSO: ≥20 mg/mL
sterility non-sterile
storage condition desiccated
storage temp. room temp
technique(s) inhibition assay: suitable
Application: N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.
Biochem/physiol Actions: N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.
Features and Benefits: This compound is featured on the Nuclear Receptors (Steroids)  and PKC  pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Packaging: 5 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352203

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