1-Deoxynojirimycin hydrochloride
SIGMA/D9305
Synonym: 1,5-
CAS Number: 73285-50-4
Empirical Formula (Hill Notation): C6H13NO4 · HCl
Molecular Weight: 199.63
MDL Number: MFCD00133247
Linear Formula: C6H13NO4 · HCl
Product Type: Chemical
| antibiotic activity spectrum | viruses |
| assay | ≥98% (TLC) |
| form | powder |
| InChI | 1S/C6H13NO4.ClH/c8-2-3-5( |
| InChI key | ZJIHMALTJRDNQI-VFQQELCFSA |
| mode of action | enzyme | inhibits |
| Quality Level | 200 ![]() |
| SMILES string | Cl[H].OC[C@H]1NC[C@H](O)[ |
| solubility | water: 19.60-20.40 mg/mL, clear, colorless |
| storage temp. | 2-8°C |
| Application: | 1-Deoxynojirimycin hydrochloride has been used • to study its effects on the loss-of-function of N-glycosylation pathway on hair cell regeneration • as an endoplasmic reticulum (ER) α-glucosidase I and II inhibitor to study its effects on TMED3-cystic fibrosis transmembrane conductance regulator (CFTR) interaction • as an insect trehalase inhibitor in TREH inhibition bioassay |
| Biochem/physiol Actions: | α-Glucosidase inhibitor |
| Biochem/physiol Actions: | 1-Deoxynojirimycin (DNJ) is a naturally occurring alkaloid azasugar or iminosugar. It is observed in mulberry leaves, Commelina communis, and bacterial strains including Bacillus and Streptomyces species. DNJ acts as an α-glucosidase inhibitor and exhibits anti-viral anti-diabetic, anti-inflammatory, anti-obesity, and antioxidant properties. |
| General description: | Chemical structure: glucosamine |
| Packaging: | 10 mg in poly bottle |
| Packaging: | 5 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352201 |

