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L-DOPS

SIGMA/D9446 - ≥98% (HPLC)

Synonym: Droxidopa; L-threo 3,4-Dihydroxyphenylserine

CAS Number: 23651-95-8
Empirical Formula (Hill Notation): C9H11NO5
Molecular Weight: 213.19
MDL Number: MFCD00799030
Linear Formula: C9H11NO5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D9446-5MG 5 mg
 $151.00
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45-D9446-25MG 25 mg
 $599.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
color white to tan
form powder
InChI 1S/C9H11NO5/c10-7(9(14)15)8(13)4-1-2-5(11)6(12)3-4/h1-3,7-8,11-13H,10H2,(H,14,15)/t7-,8+/m0/s1
InChI key QXWYKJLNLSIPIN-JGVFFNPUSA-N
Quality Level 100 
SMILES string N[C@@H]([C@H](O)c1ccc(O)c(O)c1)C(O)=O
solubility DMSO: ≥3 mg/mL
storage condition desiccated
storage temp. −20°C
Application: L-DOPS has been administered for clinical trial studies in mice with amyloid pathology.
Biochem/physiol Actions: L-DOPS is a norepinephrine precursor in vivo.
Features and Benefits: This compound is featured on the Dopamine, Norepinephrine and Epinephrine Synthesis  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
General description: L-DOPS, also called L-threo 3,4-Dihydroxyphenylserine or droxidopa is a catecholamine. L-DOPS has many clinical advantages and may be useful for treating norepinephrine deficiency. It is used for treating neurogenic orthostatic hypotension and improves norepinephrine levels. L-DOPS mediates reduction of amyloid plaques and could have a therapeutic potential for treating amyloid pathology.
Packaging: 5, 25 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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