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6-Deoxy-D-glucose

SIGMA/D9761

Synonym: D-Isorhamnose; Epifucose; Quinovose

CAS Number: 7658-08-4
Empirical Formula (Hill Notation): C6H12O5
Molecular Weight: 164.16
EC Number: 231-622-2
MDL Number: MFCD00061627
Linear Formula: C6H12O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D9761-100MG 100 mg
 $446.00
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45-D9761-250MG 250 mg
 $938.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D9761-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D9761-250MG

 

assay ≥98% (TLC)
form powder
grade Molecular Biology
InChI 1S/C6H12O5/c1-2-3(7)4(8)5(9)6(10)11-2/h2-10H,1H3/t2-,3-,4+,5-,6?/m1/s1
InChI key SHZGCJCMOBCMKK-GASJEMHNSA-N
Quality Level 200 
SMILES string C[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O
storage temp. −20°C
Application: 6-Deoxy-D-glucose has been used as a standard in the circular dichroism measurements. It has also been used as sugar to incubate starved Dictyostelium HMX44A.atg1-1 cells for microscopy studies.
Biochem/physiol Actions: 2-Deoxy-D-glucose (2-DG) is used as a glycolytic inhibitor in studying the biological function of glucose. It is not metabolized, induces endoplasmic reticulum stress and hence, blocks the carbohydrate metabolism in cancer cells. It has therapeutic potential in targeting chemo-resistant hypoxic cancer cells. 2-DG halts the N-linked glycosylation by replacing mannose.
General description: 6-Deoxy-D-glucose is a structural homolog of D-glucose (dextrose) and stable analog. It lacks the hydroxyl group at carbon 6 position. It is also an analog of mannose.
Packaging: 100, 250 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
Storage Temp. −20°C
UNSPSC 12352200

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