Dipyridamole
SIGMA/D9766 - ≥98% (HPLC)
Synonym: NSC 515776; NSC 619103
CAS Number: 58-32-2
Empirical Formula (Hill Notation): C24H40N8O4
Molecular Weight: 504.63
EC Number: 200-374-7
MDL Number: MFCD00010555
Linear Formula: C24H40N8O4
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | yellow |
| form | powder |
| InChI | 1S/C24H40N8O4/c33-15-11-3 |
| InChI key | IZEKFCXSFNUWAM-UHFFFAOYSA |
| mp | 165-166 °C (lit.) |
| originator | Boehringer Ingelheim |
| Quality Level | 200  |
| SMILES string | OCCN(CCO)c1nc(N2CCCCC2)c3 |
| solubility | DMSO: soluble |
| ethanol: soluble | |
| storage temp. | room temp |
| Application: | Dipyridamole has been used: • to perform in vitro growth inhibition assay(40) • to determine its ability to prevent uterine myometrial contractions(41) • to determine its effects on nicotinamide adenine dinucleotide (NAD+)-induced increase in intracellular adenosine triphosphate (ATP) levels(42) • to prevent nicotinamide riboside (NR)-induced axonal protection(43) |
| Biochem/physiol Actions: | Selective inhibitor of phosphodiesterase V (PDE 5); potent coronary vasodilator drug; adenosine transport inhibitor; inhibitor of platelet aggregation. |
| Features and Benefits: | This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound is featured on the Phosphodiesterases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Boehringer Ingelheim . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Dipyridamole prevents cellular uptake of adenosine. It functions as an equilibrative nucleoside transporter 1 (ENT1) inhibitor. |
| Packaging: | 1, 5, 10, 25 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| mp | 165-166 °C (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 41106305 |