MaxGel™ ECM
SIGMA/E0282 - mixture, liquid
Synonym: Human Basement Membrane Extract (BME)
Product Type: Chemical
MaxGel Human ECM enables improved expansion of Adult Keratinocytes. HaCaT cells (derived from human adult skin keratinocytes) were grown for 24 hours after plating on tissue culture plastic (A) and on 1% human ECM (B), which demonstrates that HaCaT cells proliferate better on MaxGel Human ECM.
MaxGel Human ECM enables improved expansion of Fetal Lung Fibroblasts. MRC-5 cells (derived from human fetal lung fibroblasts) were grown for 24 hours after plating on tissue culture plastic (A) and on 1% human ECM (B). As seem with other cells, MRC-5 cells propogate better on MaxGel Human ECM.
| form | liquid |
| Quality Level | 200  |
| storage temp. | −70°C |
| Application: | MaxGel™ ECM is used for the following applications: • Extracellular matrix (ECM) protein binding assays • Cell invasion assay • Cell culture |
| Application: | This product creates a three-dimensional environment that improves cellular proflieration by promoting cell growth and migration, and has been shown to aid the proliferation of many types of cells, including human embryonic stem cells, neural stem cells, neurons, glia, astrocytes, fibroblasts, hepatocytes, and keratinocytes. |
| Disclaimer: | MaxGel will remain stable for at least 1 year when stored at -70°C. |
| Legal Information: | MaxGel is a trademark of Sigma-Aldrich Co. LLC |
| Other Notes: | MaxGel ECM contains human extracellular matrix components including collagens, laminin, fibronectin, tenascin, elastin and a number of proteoglycans and glycosaminoglycans. This basement membrane extract reproduces the cooperative interactions between epithelia and mesenchyme that occur during the development and organotypic cell culture of skin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −70°C |
| UNSPSC | 12352207 |