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β-Estradiol 17-(β-D-glucuronide) sodium salt

SIGMA/E1127

Synonym: 1,3,5(10)-Estratriene-3,17β-diol 17-glucuronide; 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-glucuronide

CAS Number: 15087-02-2
Empirical Formula (Hill Notation): C24H31NaO8
Molecular Weight: 470.49
MDL Number: MFCD00056557
Linear Formula: C24H31O8Na
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-E1127-5MG 5 mg
 $103.00
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45-E1127-10MG 10 mg
 $202.00
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45-E1127-25MG 25 mg
 $342.00
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45-E1127-100MG 100 mg
 $991.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E1127-100MG.

 

assay ≥98% (HPLC)
form powder
InChI 1S/C24H32O8.Na.H/c1-24-9-8-14-13-5-3-12(25)10-11(13)2-4-15(14)16(24)6-7-17(24)31-23-20(28)18(26)19(27)21(32-23)22(29)30;;/h3,5,10,14-21,23,25-28H,2,4,6-9H2,1H3,(H,29,30);;
InChI key GPLPNZUTAJWRLU-UHFFFAOYSA-N
Quality Level 200 
shipped in ambient
SMILES string [Na].CC12CCC3C(CCc4cc(O)ccc34)C1CCC2OC5OC(C(O)C(O)C5O)C(O)=O
solubility 0.1 M NaOH: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow
sterility non-sterile
storage temp. −20°C
Application: β-Estradiol 17-(β-D-glucuronide) sodium salt has been used as a standard to determine the quantity of β-Estradiol 17-(β-D-glucuronide) during UDP-glucuronosyltransferase assay. It has also been used as a constituent of modified synthetic oviduct fluid (m-SOF) for maturation of bovine cumulus oocyte complexes (COC).
Biochem/physiol Actions: Estradiol 17-(β-D-glucuronide) (E217G) is a naturally occurring conjugated estrogen. It is formed in the liver and later excreted in bile. Increased concentrations of E217G leads to the development of cholestasis during the later stages of pregnancy, a condition which occurs with high frequency in the Dubin-Johnson syndrome.
Features and Benefits: This compound is a featured product for ADME Tox research. Click here  to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Packaging: 5, 10, 25, 100 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. −20°C
UNSPSC 51111800

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