Synonym: 1,3,5(10)-Estratriene-3,16α,17β-triol; 16α-Hydroxyestradiol; 3,16α,17β-Trihydroxy-1,3,5(10)-estratriene
CAS Number: 50-27-1
Empirical Formula (Hill Notation): C18H24O3
Molecular Weight: 288.38
EC Number: 200-022-2
MDL Number: MFCD00003691
Linear Formula: C18H24O3
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E1253-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E1253-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E1253-500MG
| assay |
≥97% |
| biological source |
synthetic (organic) |
| form |
powder |
| InChI |
1S/C18H24O3/c1-18-7-6-13-12-5-3-11(19)8-10(12)2-4-14(13)15(18)9-16(20)17(18)21/h3,5,8,13-17,19-21H,2,4,6-7,9H2,1H3/t13-,14-,15+,16-,17+,18+/m1/s1 |
| InChI key |
PROQIPRRNZUXQM-ZXXIGWHRSA-N |
| mp |
280-282 °C (lit.) |
| Quality Level |
200  |
| shipped in |
ambient |
| SMILES string |
C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1C[C@@H](O)[C@@H]2O |
| solubility |
pyridine: 50 mg/mL, clear, colorless to faintly brownish-yellow |
| sterility |
non-sterile |
| storage temp. |
room temp |
| Application: |
Estriol has been used as a sex hormone to determine its binding constants to insulin (INS), the insulin receptor (IR), and INS-like peptides derived from the IR. |
| Biochem/physiol Actions: |
Estriol is a metabolite of 17β-estradiol with much lower biological activity. It is the primary estrogen found in the urine. Large quantities of estriol and estrone are produced by the placenta during pregnancy. These are also the primary estrogens produced by adipose tissue in men and post-menopausal women. Estriol may exhibit immunomodulatory benefits against various diseases such as autoimmune, inflammatory, and neurodegenerative conditions. |
| Packaging: |
1 g in poly bottle |
| Packaging: |
100, 500 mg in poly bottle |
| Purity |
≥97% |
| mp |
280-282 °C (lit.) |
| Storage Temp. |
room temp |
| UNSPSC |
51111800 |