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β-Estradiol 17-valerate

SIGMA/E1631 - ≥98%

Synonym: 1,3,5(10)-Estratriene-3,17β-diol 17-pentanote

CAS Number: 979-32-8
Empirical Formula (Hill Notation): C23H32O3
Molecular Weight: 356.50
EC Number: 213-559-2
MDL Number: MFCD00056541
Linear Formula: C23H32O3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-E1631-1G 1 g
$241.00
1/EA
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assay ≥98%
biological source synthetic
form powder
InChI 1S/C23H32O3/c1-3-4-5-22(25)26-21-11-10-20-19-8-6-15-14-16(24)7-9-17(15)18(19)12-13-23(20,21)2/h7,9,14,18-21,24H,3-6,8,10-13H2,1-2H3
InChI key RSEPBGGWRJCQGY-UHFFFAOYSA-N
Quality Level 100 
shipped in ambient
SMILES string CCCCC(=O)OC1CCC2C3CCc4cc(O)ccc4C3CCC12C
solubility acetone: 25 mg/mL, hazy, colorless
storage temp. room temp
technique(s) ELISA: suitable
Application: β-Estradiol 17-valerate has been used:
• in an in-vivo assay, to synchronize the estrus cycle in athymic nude mice, to study the effect of recombinant pigment epithelium-derived factor (rPEDF) on induced ectopic fibroid lesions
• to study the influence of ovarian hormones on type II cGMP-dependent protein kinase (Prkg2) expression in mice
• to induce growth of estrogen-dependent tumor cells in athymic nude mice to establish a breast cancer mouse model

Biochem/physiol Actions: Estradiol valerate is observed to be useful for treating menopausal climacteric symptoms. β-Estradiol 17-valerate is used as a source of 17β-estradiol (E2) in in vitro fertilization, hormone replacement therapy, contraceptive drugs, to study reproductive disorders in animal models. It serves as growth promoter in animal farming. β-Estradiol 17-valerate is also used to culture single-sex population among fish. Studies in rats show that β-Estradiol 17-valerate has negative effects on the estrus cycle pattern.
General description: β-Estradiol 17-valerate is a synthetic estrogen.
Purity ≥98%
Storage Temp. room temp
UNSPSC 41116107

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