β-Estradiol 17-valerate
SIGMA/E1631 - ≥98%
Synonym: 1,3,5(10)
CAS Number: 979-32-8
Empirical Formula (Hill Notation): C23H32O3
Molecular Weight: 356.50
EC Number: 213-559-2
MDL Number: MFCD00056541
Linear Formula: C23H32O3
Product Type: Chemical
| assay | ≥98% |
| biological source | synthetic |
| form | powder |
| InChI | 1S/C23H32O3/c1-3-4-5-22(2 |
| InChI key | RSEPBGGWRJCQGY-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| shipped in | ambient |
| SMILES string | CCCCC(=O)OC1CCC2C3CCc4cc( |
| solubility | acetone: 25 mg/mL, hazy, colorless |
| storage temp. | room temp |
| technique(s) | ELISA: suitable |
| Application: | β-Estradiol 17-valerate has been used: • in an in-vivo assay, to synchronize the estrus cycle in athymic nude mice, to study the effect of recombinant pigment epithelium-derived factor (rPEDF) on induced ectopic fibroid lesions • to study the influence of ovarian hormones on type II cGMP-dependent protein kinase (Prkg2) expression in mice • to induce growth of estrogen-dependent tumor cells in athymic nude mice to establish a breast cancer mouse model |
| Biochem/physiol Actions: | Estradiol valerate is observed to be useful for treating menopausal climacteric symptoms. β-Estradiol 17-valerate is used as a source of 17β-estradiol (E2) in in vitro fertilization, hormone replacement therapy, contraceptive drugs, to study reproductive disorders in animal models. It serves as growth promoter in animal farming. β-Estradiol 17-valerate is also used to culture single-sex population among fish. Studies in rats show that β-Estradiol 17-valerate has negative effects on the estrus cycle pattern. |
| General description: | β-Estradiol 17-valerate is a synthetic estrogen. |
| Symbol | ![]() GHS08,GHS09 |
| Signal word | Warning |
| Hazard statements | H351 - H361fd - H362 - H410 |
| Precautionary statements | P201 - P202 - P260 - P263 - P273 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 60-61 |
| Safety Statements | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Purity | ≥98% |
| Storage Temp. | room temp |
| UNSPSC | 41116107 |



