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(+)-Etomoxir sodium salt hydrate

SIGMA/E1905 - ≥98% (HPLC), powder

Synonym: R(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt hydrate

CAS Number: 828934-41-4 (anhydrous)
Empirical Formula (Hill Notation): C15H18ClO4 · Na · H2O
Molecular Weight: 338.76
MDL Number: MFCD11044452
Linear Formula: C15H18ClO4 · Na · H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-E1905-5MG 5 mg
 $233.00
1/EA		 Add To Favorites
45-E1905-25MG 25 mg
 $800.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E1905-25MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E1905-5MG

 

assay ≥98% (HPLC)
color white
form powder
InChI 1S/C15H19ClO4.Na.H2O/c16-12-5-7-13(8-6-12)19-10-4-2-1-3-9-15(11-20-15)14(17)18;;/h5-8H,1-4,9-11H2,(H,17,18);;1H2/q;+1;/p-1/t15-;;/m1../s1
InChI key WENJLJJSJDAJDN-QCUBGVIVSA-M
Quality Level 100 
SMILES string O.[Na+].[O-]C(=O)[C@@]2(CCCCCCOc1ccc(Cl)cc1)CO2
solubility H2O: freely soluble
storage temp. 2-8°C
Application: (+)-Etomoxir sodium salt hydrate has been used as an inhibitor of carnitine palmitoyltransferase 1 (CPT-1) in breast tumor cell lines and mice tumor. It has also been used as an inhibitor of fatty acid oxidation in human primary prostate epithelial cells and lymphocytes.
Biochem/physiol Actions: Irreversible O-carnitine palmitoyltransferase-1 (CPT-1) inhibitor; PPARα activator
General description: (+)-Etomoxir sodium salt hydrate belongs to oxirane carboxylic acid group of compounds and mediates metabolic channeling of fatty acid precursors. It favors oxidative stress in T cells and prevents T cell differentiation. It inhibits fatty acid oxidation and promotes hunger and food intake. Etomoxir impairs myeloid-derived suppressor cells mediated tumor and could have potential therapeutic potential.
Packaging: 5, 25 mg in glass bottle
Packaging: Store tightly sealed, protected from exposure to light
Purity ≥98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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