ExtrAvidin®
SIGMA/E2511 - essentially salt-free, lyophilized powder
MDL Number: MFCD00163600
Product Type: Chemical
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| form | essentially salt-free, lyophilized powder |
| Quality Level | 200  |
| shipped in | wet ice |
| storage temp. | 2-8°C |
| technique(s) | dot blot: suitable |
| immunohistochemistry: suitable | |
| indirect ELISA: suitable | |
| radioimmunoassay: suitable |
| Application: | ExtrAvidin® has been used to tetramerize aliquots to generate HLA-A2 tetramers. |
| Biochem/physiol Actions: | Binding Activity: at least 10 μg biotin per mg |
| Biochem/physiol Actions: | ExtrAvidin® is prepared from egg white avidin. It is a tetrameric protein containing four high affinity binding sites for biotin. It combines the high specific activity of avidin with the low background staining of streptavidin, a biotin binding protein produced by the bacteria Streptomyces avidinii. It binds biotin with the high affinity of egg white avidin, however, it does not exhibit the unwanted non-specific binding reported for egg white avidin at physiological pH, such as the staining of mast cells. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| Legal Information: | ExtrAvidin is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | A modified form of affinity purified egg white avidin. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352203 |