Resorufin ethyl ether
SIGMA/E3763 - ≥98% (TLC), powder
Synonym: 7-
CAS Number: 5725-91-7
Empirical Formula (Hill Notation): C14H11NO3
Molecular Weight: 241.24
MDL Number: MFCD00037661
Linear Formula: C14H11NO3
Product Type: Chemical
| assay | ≥98% (TLC) |
| color | orange to red |
| form | powder |
| InChI | 1S/C23H14F5NO4.C14H11NO3/ |
| InChI key | ZOSYTBPPLWBBKM-UHFFFAOYSA |
| mp | 223-225 °C (lit.) |
| Quality Level | 200  |
| SMILES string | CCOc1ccc2N=C3C=CC(=O)C=C3 |
| solubility | chloroform: 9.80-10.20 mg/mL, clear, orange |
| storage condition | (Tightly closed. Dry) |
| storage temp. | −20°C |
| suitability | suitable for fluorescence |
| technique(s) | activity assay: suitable |
| Application: | Resorufin ethyl ether is suitable for the study of dealkylating activity of cytochrome P450 isozymes 1A1 and 1A2, where arylalkyl and alkyl isothiocyanates, and their glutathione, cysteine, and A′-acetylcysteine conjugates are used as inhibitors. It is suitable to study the ethoxyresorufin-O-deethyl |
| General description: | Fluorimetric substrate for cytochrome P450 linked enzyme, CXPIA1/2 |
| General description: | Resorufin ethers are used as markers or substrates for different cytochrome P (CYP) isoforms. Resorufin ethyl ether is the preferred resorufin ether to be metabolized by microsomes of 3-methylcholanthrene treated animals. |
| General description: | Resorufin is the reduced product of resazurin, also termed as Alamar Blu. It exhibits fluorescence at longer wavelengths and is flexible for modification in its hydroxyl group. Research area: Cell Signaling |
| Packaging: | 1, 5 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (TLC) |
| mp | 223-225 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12161501 |