(−)-Epicatechin
SIGMA/E4018 - ≥98% (HPLC), from green tea
Synonym: (−)-cis-3,3′,4′,5,7-Pentahydroxyflavane; (2R,3R)
CAS Number: 490-46-0
Empirical Formula (Hill Notation): C15H14O6
Molecular Weight: 290.27
EC Number: 207-710-1
MDL Number: MFCD00075648
Linear Formula: C15H14O6
Product Type: Chemical
| application(s) | metabolomics vitamins, nutraceuticals, and natural products |
| assay | ≥98% (HPLC) |
| biological source | green tea |
| InChI | 1S/C15H14O6/c16-8-4-11(18 |
| InChI key | PFTAWBLQPZVEMU-UKRRQHHQSA |
| mp | 240 °C (dec.) (lit.) |
| Quality Level | 200 ![]() |
| SMILES string | O[C@@H]1Cc2c(O)cc(O)cc2O[ |
| storage temp. | 2-8°C |
| Application: | (-)-Epicatechin has been used: • to examine its biological effects in cell lines from human gender-specific cancers • to study its antiviral activity • to test its ability to regenerate this enzymatic activity both in vitro at the isolated MPO−H2O2−Cl- system and ex vivo in human polymorphonuclear leukocytes (PMNs) |
| Biochem/physiol Actions: | This antioxidant is found in chocolate. (-)-Epicatechin is linked with cardiovascular effects. It is considered as a dependable standard due to its availability in cacao seeds and cocoa products. The halogenating activity of myeloperoxidase can be restored by (-)-epicatechin. |
| General description: | Epicatechin is a flavanol, that belongs to the class of secondary, polyphenolic plant metabolites. |
| Packaging: | 1, 5 mg in glass bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| mp | 240 °C (dec.) (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352205 |


