Advanced Search



Econazole nitrate salt

SIGMA/E4632

Synonym: 1-(2-[(4-Chlorophenyl)methoxy]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole

CAS Number: 24169-02-6
Empirical Formula (Hill Notation): C18H15Cl3N2O · HNO3
Molecular Weight: 444.70
EC Number: 246-053-5
MDL Number: MFCD00058160
Linear Formula: C18H15Cl3N2O · HNO3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-E4632-5G 5 g
 $0.00
1/EA
CALL FOR PRICE		 Add To Favorites
45-E4632-25G 25 g
 $335.00
1/EA		 Add To Favorites
45-E4632-100G 100 g
 $0.00
1/EA
CALL FOR PRICE		 Add To Favorites

 

antibiotic activity spectrum fungi
  Gram-positive bacteria
color white to off-white
form powder or crystals
InChI 1S/C18H15Cl3N2O.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)
InChI key DDXORDQKGIZAME-UHFFFAOYSA-N
mode of action cell membrane | interferes
  cell wall synthesis | interferes
  enzyme | inhibits
Quality Level 200 
SMILES string O[N+]([O-])=O.Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1
Application: Econazole is a broad spectrum antimycotic similar to ketoconazole. It has some action against Gram positive bacteria. It is used topically in dermatomycoses as well as orally and parenterally. It is used for studies on processes such as platelet serotonin uptake, prostanoid biosynthesis, EDHF-mediated relaxation, and Ca2+ transport pathways in thymic lymphocytes.
Biochem/physiol Actions: Econazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. Inhibition of ergosterol results in increased cellular permeability causing leakage of cellular contents. Econazole may also inhibit endogenous respiration, interact with membrane phospholipids, inhibit the transformation of yeasts to mycelial forms, inhibit purine uptake, and impair triglyceride and phospholipid biosynthesis.
General description: Chemical structure: imidazole
UNSPSC 51102829

The following items have been added to your cart:

Choose a favorite list for this item:
Catalog Number Description Price
$

Returns/Order support

Please fill out the form below if you want to request order support from Krackeler Scientific.


Quick Order

* Required


New Tariffs & Effects on Pricing

Tariff note: As we navigate the current environment of tariff surcharges and mid-year manufacturer price increases, we want to keep you informed. While we have avoided making specific decisions thus far, we anticipate that we will be forced to implement a cost adjustment policy to offset the fees we have already been absorbing. We are committed to transparency and moderation in this process.

800-334-7725
office@krackeler.com


Play Video

To Request a Quote

  1. Search or Browse for items and add to them to your Shopping Cart.
  2. Click the "Request Quote" button at the bottom of the Shopping Cart page.
  3. Fill out required fields.
  4. Optionally you can convert to standard checkout mode by choosing a payment type.
  5. Click "Request Quote" at the bottom of the page.

You will be contacted with a quote.

To Order From a Quote

  1. Register and login to the website.
  2. Receive a quote from your sales representative or customer service.
  3. Have your copy of the quote in hand.
  4. Visit our quote module to search for your quote.
Back to Top