(±)-Epinephrine hydrochloride
SIGMA/E4642
Synonym: (±)-Adrenalin; 4-
CAS Number: 329-63-5
Empirical Formula (Hill Notation): C9H13NO3 · HCl
Molecular Weight: 219.67
EC Number: 206-346-0
MDL Number: MFCD00050562
Linear Formula: C9H13NO3 · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E4642-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E4642-5G-9
| InChI | 1S/C9H13NO3.ClH/c1-10-5-9 |
| InChI key | ATADHKWKHYVBTJ-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | OC(CNC)C1=CC=C(O)C(O)=C1. |
| solubility | H2O: 50 mg/mL |
| storage temp. | 2-8°C |
| Application: | (±)-Epinephrine hydrochloride has been used: • in the induction of renalase expression in Human renal proximal tubular epithelial cells • in the infusion studies to test its effect on heart rate and eye temperature measurements in bull • as a medium supplement for the stimulation of endothelial progenitor cells |
| Biochem/physiol Actions: | Adrenergic receptor agonist. |
| Biochem/physiol Actions: | Epinephrine improves systemic pressure during cardiopulmonary resuscitation and is used post cardiac arrest. The levels of epinephrine increases during trauma, sepsis and hypoglycemia resulting in increased cardiac rate and contractility. It is used in the treatment of acute anaphylaxis. Use of epinephrine hydrochloride enables dilation of pupil during intraocular lens (IOL) implantation surgery. |
| General description: | Epinephrine (adrenalin) is synthesized from norepinephrine (noradrenalin) by the action of the enzyme phenylethanolamine N-methyltransferase. Epinephrine comprises 5%-10% of the total catecholamines in the central nervous system. It is a mixed α/β-adrenergic receptor agonist and stimulates these receptors. Their site of synthesis is adrenal medulla and it travels through the vascular systems. Its breakdown occurs in the central nervous system (CNS), liver and kidney. |
| Other Notes: | The ratio of +/- adrenaline is not determined. |
| Packaging: | 5, 25 g in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 + H311 - H315 - H319 - H335 |
| Precautionary statements | P280 - P301 + P310 + P330 - P302 + P352 + P312 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 24/25-36/37/38 |
| Safety Statements | 26-36/37-45 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |