Epinastine hydrochloride
SIGMA/E5156 - ≥98% (HPLC), solid
Synonym: 9,13b-Dihydro-1H-
CAS Number: 108929-04-0
Empirical Formula (Hill Notation): C16H15N3 · HCl
Molecular Weight: 285.77
MDL Number: MFCD00933434
Linear Formula: C16H15N3 · HCl
Product Type: Chemical
| assay | ≥98% (HPLC) |
| color | white |
| form | solid |
| InChI | 1S/C16H15N3.ClH/c17-16-18 |
| InChI key | VKXSGUIOOQPGAF-UHFFFAOYSA |
| originator | Boehringer Ingelheim |
| Quality Level | 100 ![]() |
| SMILES string | Cl[H].NC1=NCC2N1c3ccccc3C |
| solubility | H2O: 38 mg/mL |
| storage condition | desiccated |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Epinastine hydrochloride is a non-sedating H1 histamine receptor antagonist. |
| Features and Benefits: | This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Boehringer Ingelheim . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Epinastine has antihistamine functions. In mast cells, it may modulate cytokine and chemokine production. In dendritic cells, it controls T helper cell mediated immune response. Epinastine hydrochloride does not traverse the brain barrier. Oral dosage of epinastine hydrochloride is prescribed for children with sleep-disordered breathing (SDB) and nasal inflammation. Ophthalmic solution of epinastine is effective for allergic conjunctivitis. |
| Packaging: | 10, 50 mg in glass bottle |
| Symbol | GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264 - P270 - P301 + P310 - P405 - P501 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |


