Ethylenediaminetetraacetic acid tetrasodium salt hydrate

SIGMA/E5391 - ≥99.0%

Synonym: EDTA tetrasodium salt; Edathamil; Tetrasodium ethylenediaminetetraacetate hydrate

CAS Number: 194491-31-1
Empirical Formula (Hill Notation): C₁₀H₁₂N₂Na₄O₈ · xH₂O
Molecular Weight: 380.17 (anhydrous basis)
EC Number: 200-573-9
MDL Number: MFCD00150025
Linear Formula: (NaOOCCH₂)₂NCH₂CH₂N(CH₂COONa)₂ · xH₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-E5391-250G	250 g	$99.80 1/EA	Add To Favorites
45-E5391-1KG	1 kg	$308.00 1/EA	Add To Favorites
45-E5391-20KG	20 kg	$4470.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E5391-250G

Properties
Descriptions
Safety Info.
Basic Data

absorption	≤0.06 at 280 in H₂O at 0.1 M
	≤1.5 at 260 in H₂O at 0.1 M
anion traces	chloride (Cl^-): ≤0.05%
	sulfate (SO₄^2-): ≤0.01%
application(s)	sample preparation
assay	≥99.0%
biological source	synthetic (organic)
cation traces	Al: ≤0.001%
	As: ≤0.0001%
	Ba: ≤0.0005%
	Bi: ≤0.0005%
	Ca: <0.001%
	Cd: ≤0.0005%
	Co: ≤0.0005%
	Cr: ≤0.0005%
	Cu: ≤0.0005%
	Fe: ≤0.0005%
	Li: ≤0.0005%
	Mg: ≤0.0005%
	Mn: ≤0.0005%
	Mo: ≤0.0005%
	Ni: ≤0.0005%
	Pb: ≤0.0005%
	Sr: ≤0.0005%
	Zn: ≤0.0005%
form	powder
impurities	Insoluble matter, passes filter test
InChI	1S/C10H16N2O8.4Na.H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;1H2/q;4*+1;/p-4
InChI key	GXFFSKMBMYHTAE-UHFFFAOYSA-J
pH	11.0-12.0 (0.1 M in H₂O)
Quality Level	200
SMILES string	O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
solubility	H₂O: 0.1 M, clear, colorless
storage temp.	room temp
technique(s)	ligand binding assay: suitable

Application:	EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.
Application:	Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.
Preparation Note:	Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.

Symbol	GHS05,GHS07,GHS08
Signal word	Danger
Hazard statements	H302 + H332 - H318 - H373
Precautionary statements	P280 - P301 + P312 + P330 - P304 + P340 + P312 - P305 + P351 + P338 + P310 - P314
Hazard Codes	Xn
Risk Statements	22-41
Safety Statements	26-39-46
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99.0%
Storage Temp.	room temp
UNSPSC	12352204

To Order From a Quote