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β-Estradiol 6-(O-carboxy­methyl)oxime: BSA

SIGMA/E5630

MDL Number: MFCD03613560
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-E5630-5MG 5 mg
 $231.00
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45-E5630-10MG 10 mg
 $397.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E5630-10MG

 

extent of labeling ~30 mol steroid per mol BSA
form lyophilized powder
Quality Level 200 
shipped in ambient
solubility phosphate buffer: 0.90-1.10 mg/mL, faintly hazy to hazy, colorless to faintly yellow
sterility non-sterile
storage temp. 2-8°C
Application: β-Estradiol 6-(O-carboxy­methyl)oxime: BSA has been used:
• to test its effect on the N-methyl-D-aspartate receptor (NMDAR) currents in female dorsal root ganglion (DRG) neurons
• to coat microplates for the detection of plasma 17β-Estradiol levels using indirect enzyme-linked immunosorbent assay (ELISA)
• to test its effect on MutL homolog 1 in colorectal cancer lines
Biochem/physiol Actions: β-Estradiol 6-(O-carboxy­methyl)oxime: BSA mimics estrogen and favors amyloid precursor protein α (sAPPα) secretion in vitro studies with primary rat cortical neurons. It also stimulates mitogen-activated protein kinase (MAPK) activity in human umbilical vein endothelial cells
General description: β-Estradiol 6-(O-carboxy­methyl)oxime: BSA is an estradiol conjugate and is membrane-impermeable. BSA is linked to the estradiol at position 6 to form the β-estradiol 6-(O-carboxymethyl) oxime: BSA conjugate.
Packaging: 5, 10, 25 mg in glass bottle
Storage Temp. 2-8°C
UNSPSC 51111800

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