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Etomidate

SIGMA/E6530 - >98% (HPLC), powder

Synonym: (R)-1-(α-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester; Amidate; R16659

CAS Number: 33125-97-2
Empirical Formula (Hill Notation): C14H16N2O2
Molecular Weight: 244.29
EC Number: 251-385-9
MDL Number: MFCD00869295
Linear Formula: C14H16N2O2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-E6530-10MG 10 mg
$184.00
1/EA
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45-E6530-50MG 50 mg
$774.00
1/EA
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assay >98% (HPLC)
color white
form powder
InChI 1S/C14H16N2O2/c1-3-18-14(17)13-9-15-10-16(13)11(2)12-7-5-4-6-8-12/h4-11H,3H2,1-2H3/t11-/m1/s1
InChI key NPUKDXXFDDZOKR-LLVKDONJSA-N
originator Johnson & Johnson
Quality Level 100 
SMILES string CCOC(=O)c1cncn1[C@H](C)c2ccccc2
solubility DMSO: >10 mg/mL
storage temp. 2-8°C
Biochem/physiol Actions: Etomidate is a general anesthetic; potentiates GABAA transmission
Biochem/physiol Actions: Etomidate is a general anesthetic; potentiates GABAA transmission. The possible neuroprotective effect of etomidate against streptozotocin-induced (STZ-induced) hyperglycaemia were investigated in the rat brain and spinal cord. Etomidate treatment demonstrated neuroprotective effect on the neuronal tissue against the diabetic oxidative damage
Features and Benefits: This compound is a featured product for Neuroscience research. Click here  to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Etomidate is an imidazole derivative, which functions as an nonbarbiturate hypnotic agent. It is used in speech and memory test. Etomidate regulates hemodynamic stability by preserving sympathetic outflow and autonomic reflexes. It inhibits adrenal steroidogenesis.
Packaging: 10, 50 mg in glass bottle
Symbol GHS07GHS09  GHS07,GHS09
Signal word Warning
Hazard statements H302 - H410
Precautionary statements P273 - P301 + P312 + P330
Hazard Codes Xn
Risk Statements 22
Safety Statements 36
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity >98% (HPLC)
Storage Temp. 2-8°C
UNSPSC 12352200

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