Etomidate
SIGMA/E6530 - >98% (HPLC), powder
Synonym: (R)-1-(α-Methylbenzyl)imidazole-5-carboxylic acid ethyl ester; Amidate; R16659
CAS Number: 33125-97-2
Empirical Formula (Hill Notation): C14H16N2O2
Molecular Weight: 244.29
EC Number: 251-385-9
MDL Number: MFCD00869295
Linear Formula: C14H16N2O2
Product Type: Chemical
| assay | >98% (HPLC) |
| color | white |
| form | powder |
| InChI | 1S/C14H16N2O2/c1-3-18-14( |
| InChI key | NPUKDXXFDDZOKR-LLVKDONJSA |
| originator | Johnson & Johnson |
| Quality Level | 100 ![]() |
| SMILES string | CCOC(=O)c1cncn1[C@H](C)c2 |
| solubility | DMSO: >10 mg/mL |
| storage temp. | 2-8°C |
| Biochem/physiol Actions: | Etomidate is a general anesthetic; potentiates GABAA transmission |
| Biochem/physiol Actions: | Etomidate is a general anesthetic; potentiates GABAA transmission. The possible neuroprotective effect of etomidate against streptozotocin-induced (STZ-induced) hyperglycaemia were investigated in the rat brain and spinal cord. Etomidate treatment demonstrated neuroprotective effect on the neuronal tissue against the diabetic oxidative damage |
| Features and Benefits: | This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Features and Benefits: | This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| General description: | Etomidate is an imidazole derivative, which functions as an nonbarbiturate hypnotic agent. It is used in speech and memory test. Etomidate regulates hemodynamic stability by preserving sympathetic outflow and autonomic reflexes. It inhibits adrenal steroidogenesis. |
| Packaging: | 10, 50 mg in glass bottle |
| Symbol | ![]() GHS07,GHS09 |
| Signal word | Warning |
| Hazard statements | H302 - H410 |
| Precautionary statements | P273 - P301 + P312 + P330 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| RIDADR | UN 3077 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | >98% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |



