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cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt

SIGMA/E6627 - ≥99% (capillary GC)

CAS Number: 73167-03-0
Empirical Formula (Hill Notation): C20H29NaO2
Molecular Weight: 324.43
MDL Number: MFCD00079184
Linear Formula: CH3(CH2CH=CH)5(CH2)3CO2Na
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-E6627-5MG 5 mg
 $63.30
1/EA		 Add To Favorites
45-E6627-25MG 25 mg
 $235.00
1/EA		 Add To Favorites

 

assay ≥99% (capillary GC)
biological source synthetic (organic)
color white to off-white
form film or powder
InChI 1S/C20H30O2.Na.H/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22;;/h3-4,6-7,9-10,12-13,15-16H,2,5,8,11,14,17-19H2,1H3,(H,21,22);;/b4-3-,7-6-,10-9-,13-12-,16-15-;;
InChI key TVEGTERCKGGVCJ-LIJGWLRISA-N
Quality Level 200 
shipped in dry ice
SMILES string [Na].CCC=C/CC=C/CC=C/CC=C/CC=C/CCCC(O)=O
solubility methanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
storage temp. −20°C
Application: cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt has been used:
• to study its effect on the pathology of lupus in drug-induced and spontaneous mouse models
• to pretreat mouse alveolar macrophages to study the effect/relationship between amiodarone and eicosapentaenoic acid (EPA) concerning the cytokine release
• to examine if pharmacological correction with EPA supplementation might restore autophagic flux and reduce renal lipotoxicity in mice
Biochem/physiol Actions: 5-Lipoxygenase inhibitor; reduces thromboxane A2 production.
Biochem/physiol Actions: Eicosapentaenoic acid (EPA) possesses anti-hyperglycemic, anti-oxidant, anti-hyperlipidemic, and anti-inflammatory properties. It aids in improving vasoreactivity. EPA is capable of suppressing vascular smooth muscle proliferation. It ameliorates pulmonary hypertension by preventing Fyn kinase activity. EPA exhibits a beneficial effect on lipid metabolism. It is used to treat hypercholesterolemia and atherosclerosis.
General description: Eicosapentaenoic acid (EPA)/timnodonic acid is an omega-3 polyunsaturated fatty acid (PUFA). This long-chain fatty acid is mainly found in fish oil.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99% (capillary GC)
Storage Temp. −20°C
UNSPSC 12352211

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