Ethylenediaminetetraacetic acid

SIGMA/E6758 - anhydrous, crystalline, BioReagent, suitable for cell culture

Synonym: (Ethylenedinitrilo)tetraacetic acid; EDTA; Edathamil; Ethylenedinitrilotetraacetic acid

CAS Number: 60-00-4
Empirical Formula (Hill Notation): C₁₀H₁₆N₂O₈
Molecular Weight: 292.24
EC Number: 200-449-4
MDL Number: MFCD00003541
Linear Formula: (HO₂CCH₂)₂NCH₂CH₂N(CH₂CO₂H)₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-E6758-100G	100 g	$44.30 1/EA	Add To Favorites
45-E6758-500G	500 g	$133.00 1/EA	Add To Favorites

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This image depicts SKU: E6758-100G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98.5%
cation traces	C: 40.7-41.5%
	N: 9.3-9.8%
density	1.46 g/cm³ at 20 °C
form	crystalline
grade	anhydrous
InChI	1S/C10H16N2O8/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20)
InChI key	KCXVZYZYPLLWCC-UHFFFAOYSA-N
mp	250 °C (dec.) (lit.)
pH	2.5 (23 °C, 10 g/L)
product line	BioReagent
Quality Level	200
reaction suitability	reagent type: chelator
SMILES string	OC(=O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
solubility	3 M NaOH: 100 mg/mL
technique(s)	cell culture \| mammalian: suitable

Application:	Ethylenediaminetetraacetic acid has been used: • as a component of peptide dilution buffer for intracellular BH3 (Bcl-2 homology (BH) domain) profiling and validation • as a medium component in the hepatic stellate cell (HSCs) culture • as a component of homogenization buffer for protein extraction from eye tissues • for stopping benzonase reaction in lysis buffer
Biochem/physiol Actions:	Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood samples. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline imparts serves as root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium Disodium EDTA administration is effective in slowing down the progression of chronic kidney disease.
Packaging:	100, 500 g in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H319
Precautionary statements	P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36
Safety Statements	26
RIDADR	UN 3077 9 / PGIII
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.5%
mp	250 °C (dec.) (lit.)
Density	1.46 g/cm³ at 20 °C
UNSPSC	12161700

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