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Enalapril maleate salt

SIGMA/E6888 - powder, ≥98% (TLC)

Synonym: (S)-N-[1-(Ethoxycarbonyl)-3-phenylpropyl]-Ala-Pro maleate salt

CAS Number: 76095-16-4
Empirical Formula (Hill Notation): C20H28N2O5 · C4H4O4
Molecular Weight: 492.52
EC Number: 278-375-7
Linear Formula: C20H28N2O5 · C4H4O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-E6888-250MG 250 mg
 $62.80
1/EA		 Add To Favorites
45-E6888-1G 1 g
 $171.00
1/EA		 Add To Favorites
45-E6888-5G 5 g
 $592.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E6888-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E6888-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E6888-5G

 

assay ≥98% (TLC)
color white to off-white
form powder
InChI 1S/C21H30N2O5.C4H4O5/c1-3-28-19(24)14-17(12-11-16-8-5-4-6-9-16)22-15(2)20(25)23-13-7-10-18(23)21(26)27;5-3(6)1-2-4(7)9-8/h4-6,8-9,15,17-18,22H,3,7,10-14H2,1-2H3,(H,26,27);1-2,8H,(H,5,6)/b;2-1-/t15-,17-,18-;/m0./s1
InChI key UQKQUZOIQFOJOI-KJHLASMFSA-N
originator Merck & Co., Inc., Kenilworth, NJ, U.S.
Quality Level 100 
SMILES string C[C@@H](C(N1[C@H](C(O)=O)CCC1)=O)N[C@H](CC(OCC)=O)CCC2=CC=CC=C2.O=C(OO)/C=CC(O)=O
solubility methanol: ≥50 mg/mL, clear, colorless to yellow
Application: Enalapril maleate salt has been used:
• to reduce albumin excretion rate (AER) and glomerular lesions
• to examine the effects of enalapril pre-treatment on myocardial injury
• to investigate its efficacious doses and schedules for mitigation of radiation lung injury
Biochem/physiol Actions: A long-acting angiotensin-converting enzyme inhibitor.
Features and Benefits: This compound is a featured product for ADME Tox research. Click here  to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S. . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Enalapril is an angiotensin-converting enzyme inhibitor. It is used to treat heart failure and high blood pressure.
Packaging: 1, 5 g in poly bottle
Packaging: 250 mg in poly bottle
Purity ≥98% (TLC)
UNSPSC 12352200

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