Ethosuximide
SIGMA/E7138
Synonym: 2-
CAS Number: 77-67-8
Empirical Formula (Hill Notation): C7H11NO2
Molecular Weight: 141.17
EC Number: 201-048-7
MDL Number: MFCD00072123
Linear Formula: C7H11NO2
Product Type: Chemical
| InChI | 1S/C7H11NO2/c1-3-7(2)4-5( |
| InChI key | HAPOVYFOVVWLRS-UHFFFAOYSA |
| Quality Level | 100 ![]() |
| SMILES string | O=C1NC(CC1(C)CC)=O |
| solubility | ethanol: 100 mg/mL |
| Application: | Ethosuximide has been used: • to confirm its effect on spike wave discharges (SWD) in rats • to examine its effects on spontaneous locomotion and anxiety-related thigmotaxis behaviours in zebrafish larvae of wild type • as a model drug for the treatment of epilepsy in vivo(4) |
| Biochem/physiol Actions: | Ethosuximide is an anticonvulsant drug and an antagonist for T-type calcium channel. It is known to prevent spike wave discharges, characterized in absence seizures. |
| Features and Benefits: | This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Packaging: | 5, 100 g in glass bottle |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264 - P270 - P301 + P312 - P501 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| Safety Statements | 36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352111 |


