Synonym: 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol
CAS Number: 304684-77-3
Empirical Formula (Hill Notation): C18H18N4O2S
Molecular Weight: 354.43
MDL Number: MFCD00380179
Linear Formula: C18H18N4O2S
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
yellow |
| form |
powder |
| InChI |
1S/C18H18N4O2S/c1-24-14-8-11(6-7-13(14)23)9-21-22-17-16-12-4-2-3-5-15(12)25-18(16)20-10-19-17/h6-10,23H,2-5H2,1H3,(H,19,20,22)/b21-9+ |
| InChI key |
VFNUTEMVQGLDAG-ZVBGSRNCSA-N |
| Quality Level |
100  |
| SMILES string |
COc1cc(ccc1O)C=NNc2ncnc3sc4CCCCc4c23 |
| solubility |
DMSO: >20 mg/mL |
| storage temp. |
2-8°C |
| Biochem/physiol Actions: |
Exo2 acts as a chemical probe of intracellular transport. |
| Biochem/physiol Actions: |
Exo2 acts as a chemical probe of intracellular transport. Edxo2 has activities similar to Brefeldin A with membrane trafficking to the Golgi appartus, but appears more selective. |
| Biochem/physiol Actions: |
Exo2 is a bioactive small molecule that activates Golgi-endoplasmic reticulum (ER) fusion in mammals by distorting the Golgi apparatus. It prevents the release of secretory cargo from the ER. Exo2 do not modify the morphology of the trans-Golgi network (TGN). It also inhibits the anterograde movement of vesicular stomatitis virus G (VSV G) glycoprotein, from ER to Golgi. |
| Packaging: |
5, 25 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
2-8°C |
| UNSPSC |
12352200 |
