Exo2

SIGMA/E7159 - ≥98% (HPLC)

Synonym: 2-Methoxy-4-[(5,6,7,8-tetrahydro-benzo[4,5]thieno[2,3-d]pyrimidin-4-yl)-hydrazonomethyl]-phenol

CAS Number: 304684-77-3
Empirical Formula (Hill Notation): C₁₈H₁₈N₄O₂S
Molecular Weight: 354.43
MDL Number: MFCD00380179
Linear Formula: C₁₈H₁₈N₄O₂S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-E7159-5MG	5 mg	$106.05 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
color	yellow
form	powder
InChI	1S/C18H18N4O2S/c1-24-14-8-11(6-7-13(14)23)9-21-22-17-16-12-4-2-3-5-15(12)25-18(16)20-10-19-17/h6-10,23H,2-5H2,1H3,(H,19,20,22)/b21-9+
InChI key	VFNUTEMVQGLDAG-ZVBGSRNCSA-N
Quality Level	100
SMILES string	COc1cc(ccc1O)C=NNc2ncnc3sc4CCCCc4c23
solubility	DMSO: >20 mg/mL
storage temp.	2-8°C

Biochem/physiol Actions:	Exo2 acts as a chemical probe of intracellular transport.
Biochem/physiol Actions:	Exo2 acts as a chemical probe of intracellular transport. Edxo2 has activities similar to Brefeldin A with membrane trafficking to the Golgi appartus, but appears more selective.
Biochem/physiol Actions:	Exo2 is a bioactive small molecule that activates Golgi-endoplasmic reticulum (ER) fusion in mammals by distorting the Golgi apparatus. It prevents the release of secretory cargo from the ER. Exo2 do not modify the morphology of the trans-Golgi network (TGN). It also inhibits the anterograde movement of vesicular stomatitis virus G (VSV G) glycoprotein, from ER to Golgi.
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352200

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