Synonym: 1,3,5(10)-Estratriene-3,17β-diol 17-acetate; 3,17β-Dihydroxy-1,3,5(10)-estratriene 17-acetate
CAS Number: 1743-60-8
Empirical Formula (Hill Notation): C20H26O3
Molecular Weight: 314.42
MDL Number: MFCD00056537
Linear Formula: C20H26O3
Product Type: Chemical
| assay |
≥99% |
| form |
powder |
| InChI |
1S/C20H26O3/c1-12(21)23-19-8-7-18-17-5-3-13-11-14(22)4-6-15(13)16(17)9-10-20(18,19)2/h4,6,11,16-19,22H,3,5,7-10H2,1-2H3/t16-,17-,18+,19+,20+/m1/s1 |
| InChI key |
QAHOQNJVHDHYRN-SLHNCBLASA-N |
| Quality Level |
200  |
| shipped in |
ambient |
| SMILES string |
CC(=O)O[C@H]1CC[C@H]2[C@@H]3CCc4cc(O)ccc4[C@H]3CC[C@]12C |
| solubility |
chloroform: 50 mg/mL, clear, colorless to faintly brownish-yellow |
| sterility |
non-sterile |
| storage temp. |
room temp |
| Application: |
β-Estradiol 17-acetate has been used in body burden analyses, to study the effect of triclosan on an estuarine fish. |
| Biochem/physiol Actions: |
β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, and hence is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease. |
| Features and Benefits: |
This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| Symbol |
 GHS08 |
| Signal word |
Danger |
| Hazard statements |
H360 |
| Precautionary statements |
P201 - P308 + P313 |
| Hazard Codes |
T |
| Risk Statements |
60-61 |
| Safety Statements |
53-45 |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥99% |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |
