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Esmolol hydrochloride

SIGMA/E8031 - ≥98% (HPLC), solid

Synonym: 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester hydrochloride hydrochloride

CAS Number: 81161-17-3
Empirical Formula (Hill Notation): C16H26NClO4
Molecular Weight: 331.83
MDL Number: MFCD00941432
Linear Formula: C16H26NClO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-E8031-10MG 10 mg
 $147.00
1/EA		 Add To Favorites
45-E8031-50MG 50 mg
 $630.00
1/EA		 Add To Favorites

 

assay ≥98% (HPLC)
form solid
InChI 1S/C16H25NO4.ClH/c1-12(2)17-10-14(18)11-21-15-7-4-13(5-8-15)6-9-16(19)20-3;/h4-5,7-8,12,14,17-18H,6,9-11H2,1-3H3;1H
InChI key GEKNCWBANDDJJL-UHFFFAOYSA-N
mp 89.0-90.6 °C
originator Baxter
Quality Level 100 
SMILES string Cl.COC(=O)CCc1ccc(OCC(O)CNC(C)C)cc1
solubility H2O: 12 mg/mL
storage condition desiccated
storage temp. 2-8°C
Application: Esmolol hydrochloride (ESM) may be used as a standard in spectrophotometric and electrochemical method for the determination of ESM in biological samples and pharmaceutical formulations.
Biochem/physiol Actions: Esmolol hydrochloride (ESM) is a class II antiarrhythmic drug. It is used to decrease the force and rate of heart contractions during surgery. Overdose of ESM can lead to side effects such as bradycardia, cardiac arrest, hypoventilation, mood disorder, and coma.
Biochem/physiol Actions: Esmolol hydrochloride is a ultrashort-acting β1 adrenoceptor antagonist (β1 receptor occupancy = 84.7%).
Features and Benefits: This compound is featured on the β-Adrenoceptors  page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here .
Features and Benefits: This compound was developed by Baxter . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 10, 50 mg in glass bottle
Risk Statements 52/53
Safety Statements 61
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
mp 89.0-90.6 °C
Storage Temp. 2-8°C
UNSPSC 12352200

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