5-Ethyl-2′-deoxyuridine
SIGMA/E9386
Synonym: EUdR; Edoxudine
CAS Number: 15176-29-1
Empirical Formula (Hill Notation): C11H16N2O5
Molecular Weight: 256.26
EC Number: 239-226-1
MDL Number: MFCD00079191
Linear Formula: C11H16N2O5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E9386-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E9386-250MG
| assay | ≥95% (HPLC) |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C11H16N2O5/c1-2-6-4-13 |
| InChI key | XACKNLSZYYIACO-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | CCC1=CN(C2CC(O)C(CO)O2)C( |
| solubility | water: 50 mg/mL, clear, colorless to yellow |
| storage temp. | −20°C |
| Biochem/physiol Actions: | 5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (FU) modulator. EtdUrd may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels. |
| Biochem/physiol Actions: | 5-Ethyl-2′-deoxyuridine is an analog of pyrimidine, uridine. It is an effective antiviral agent and inhibits cell division in leukemic tumor cells. 5-Ethyl-2′-deoxyuridine interacts with 2′-deoxycytidine phosphate (dCTP) biosynthesis pathway to elicit antiproliferative effects. |
| Other Notes: | Homolog of thymidine |
| Packaging: | 1 g in poly bottle |
| Packaging: | 250 mg in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 41106305 |