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5-Ethyl-2′-deoxyuridine

SIGMA/E9386

Synonym: EUdR; Edoxudine

CAS Number: 15176-29-1
Empirical Formula (Hill Notation): C11H16N2O5
Molecular Weight: 256.26
EC Number: 239-226-1
MDL Number: MFCD00079191
Linear Formula: C11H16N2O5
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-E9386-250MG 250 mg
$365.00
1/EA
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45-E9386-1G 1 g
$896.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E9386-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E9386-250MG

 

assay ≥95% (HPLC)
biological source synthetic (organic)
form powder
InChI 1S/C11H16N2O5/c1-2-6-4-13(11(17)12-10(6)16)9-3-7(15)8(5-14)18-9/h4,7-9,14-15H,2-3,5H2,1H3,(H,12,16,17)
InChI key XACKNLSZYYIACO-UHFFFAOYSA-N
Quality Level 200 
SMILES string CCC1=CN(C2CC(O)C(CO)O2)C(=O)NC1=O
solubility water: 50 mg/mL, clear, colorless to yellow
storage temp. −20°C
Biochem/physiol Actions: 5-Ethyl-2′-deoxyuridine (EUdR) is used as a 5-fluorouracil (FU) modulator. EtdUrd may be used to enhance the therapeutic index of 5-FU by reducing the catabolism, prolonging the plasma and intratumoral concentrations of 5-FU, and offering protection to normal organs by increasing the endogenous uridine levels.
Biochem/physiol Actions: 5-Ethyl-2′-deoxyuridine is an analog of pyrimidine, uridine. It is an effective antiviral agent and inhibits cell division in leukemic tumor cells. 5-Ethyl-2′-deoxyuridine interacts with 2′-deoxycytidine phosphate (dCTP) biosynthesis pathway to elicit antiproliferative effects.
Other Notes: Homolog of thymidine
Packaging: 1 g in poly bottle
Packaging: 250 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95% (HPLC)
Storage Temp. −20°C
UNSPSC 41106305

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