Synonym: 1,3,5(10)-Estratriene-3,17β-diol 3-sulfate; 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-sulfate
CAS Number: 4999-79-5
Empirical Formula (Hill Notation): C18H23NaO5S
Molecular Weight: 374.43
MDL Number: MFCD00056553
Linear Formula: C18H23O5SNa
Product Type: Chemical
| assay |
≥93% |
| contains |
~70% N-methyl-D-glucamine as stabilizer |
| form |
powder |
| InChI |
1S/C18H24O5S.Na.H/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;;/h3,5,10,14-17,19H,2,4,6-9H2,1H3,(H,20,21,22);;/t14-,15-,16+,17+,18+;;/m1../s1 |
| InChI key |
PYPVMTJYMKHIST-LBARCDFESA-N |
| Quality Level |
200  |
| shipped in |
ambient |
| SMILES string |
[Na].[H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24 |
| solubility |
methanol: 9.80-10.20 mg/mL, clear, colorless to faintly yellow |
| sterility |
non-sterile |
| storage temp. |
room temp |
| Application: |
β-Estradiol 3-sulfate sodium salt has been used to measure the estradiol level from culture supernatant in ultra-performance liquid chromatography-tandem mass spectrometry. |
| Biochem/physiol Actions: |
β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, hence it is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease. |
| General description: |
β-Estradiol is secreted by developing ovaries and is predominant during premenopause in women. |
| Packaging: |
100 mg in glass bottle |
| Packaging: |
25 mg in poly bottle |
| Packaging: |
Package size based on steroid content |
| Purity |
≥93% |
| Storage Temp. |
room temp |
| UNSPSC |
51111800 |
GHS07,GHS08