MISSION® esiRNA
SIGMA/EMU036241 - targeting mouse Ap1m2
Product Type: Product-on-demand
| description | Powered by Eupheria Biotech |
| Ensembl | mouse accession no. | ENSMUSG00000003309 ![]() |
| esiRNA cDNA target sequence | ATCACACAACAGGGCAACAAGCTGG |
| form | lyophilized powder |
| NCBI accession no. | NM_009678 ![]() |
| product line | MISSION® |
| Quality Level | 100 ![]() |
| shipped in | ambient |
| storage temp. | −20°C |
| Biochem/physiol Actions: | Ap1m2 (AP-1 complex subunit μ-2) is a μ1B subunit of AP-1B (adaptor protein). In polarised epithelial cells, AP-1B is responsible for basolateral sorting of membrane proteins. Absence of the Ap1m2 gene in mice results in T-helper (Th)17-dominant colitis and intestinal epithelial cell hyperplasia. Ap1m2 is associated with expression of antimicrobial proteins and the luminal transport of secretory IgA (immunoglobulin A). |
| General description: | MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing. For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA . |
| Legal Information: | MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany |
| RIDADR | NONH for all modes of transport |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 41105324 |

