Fenvalerate
SIGMA/F1428 - ≥97%
Synonym: α-Cyano-3-phenoxybenzyl α-(4-chlorophenyl)isovalerate
CAS Number: 51630-58-1
Empirical Formula (Hill Notation): C25H22ClNO3
Molecular Weight: 419.90
MDL Number: MFCD00055324
Linear Formula: C25H22ClNO3
Product Type: Chemical
| assay | ≥97% |
| InChI | 1S/C25H22ClNO3/c1-17(2)24 |
| InChI key | NYPJDWWKZLNGGM-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | CC(C)C(C(=O)OC(C#N)c1cccc |
| storage temp. | −20°C |
| Application: | Fenvalerate has been used to study the effect of Fen exposure on reproductive functions. |
| Biochem/physiol Actions: | Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes. |
| Biochem/physiol Actions: | Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell. |
| Biochem/physiol Actions: | Type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B). |
| General description: | Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers. |
| Preparation Note: | Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone. |
| Symbol | ![]() GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 - H315 - H319 - H335 - H410 |
| Precautionary statements | P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | T,N |
| Risk Statements | 25-36/37/38-50/53 |
| Safety Statements | 26-45-61 |
| RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |



