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Fenvalerate

SIGMA/F1428 - ≥97%

Synonym: α-Cyano-3-phenoxybenzyl α-(4-chlorophenyl)­iso­valerate

CAS Number: 51630-58-1
Empirical Formula (Hill Notation): C25H22ClNO3
Molecular Weight: 419.90
MDL Number: MFCD00055324
Linear Formula: C25H22ClNO3
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-F1428-25MG 25 mg
$171.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F1428-25MG

 

assay ≥97%
InChI 1S/C25H22ClNO3/c1-17(2)24(18-11-13-20(26)14-12-18)25(28)30-23(16-27)19-7-6-10-22(15-19)29-21-8-4-3-5-9-21/h3-15,17,23-24H,1-2H3
InChI key NYPJDWWKZLNGGM-UHFFFAOYSA-N
Quality Level 200 
SMILES string CC(C)C(C(=O)OC(C#N)c1cccc(Oc2ccccc2)c1)c3ccc(Cl)cc3
storage temp. −20°C
Application: Fenvalerate has been used to study the effect of Fen exposure on reproductive functions.
Biochem/physiol Actions: Fenvalerate has good insecticidal potential and is less toxic to animals. It might cause endocrine disruption and reproductive dysfunction in humans. Metabolism of fenvalerate includes oxidation, ester cleavage and conjugation reaction. It is stable at pH 5 and 7, while it gets hydrolyzed at pH 9. In rat models it is found to hinder the action of mitochondrial enzymes.
Biochem/physiol Actions: Fenvalerate is a type II semi-synthetic pyrethrin, which acts as a potent inhibitor of calcineurin (protein phosphatase 2B). This inhibitory action results in cellular hyperexcitability by causing non-mutated calcium channels to remain open for an extended period of time allowing an abundance of Ca2+ to enter the cell.
Biochem/physiol Actions: Type II pyrethroid. Potent inhibitor of calcineurin (protein phosphatase 2B).
General description: Fenvalerate an ester molecule, exists in four stereoisomers with two chiral centers.
Preparation Note: Fenvalerate has been reported to be soluble in DMSO, ethanol, and acetone.
Purity ≥97%
Storage Temp. −20°C
UNSPSC 12352200

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