Flt-3/Flk-2 ligand human
SIGMA/F3422 - recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture, ≥98% (SDS-PAGE and HPLC)
Synonym: FL
MDL Number: MFCD01093789
Product Type: Chemical
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| assay | ≥98% (SDS-PAGE and HPLC) |
| biological source | human |
| form | lyophilized powder |
| impurities | endotoxin, tested |
| mol wt | 17.6 kDa |
| packaging | pkg of 5 μg |
| potency | ≤1.0 ng/mL |
| Quality Level | 100  |
| recombinant | expressed in E. coli |
| storage condition | avoid repeated freeze/thaw cycles |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | P36888  |
| Analysis Note: | The biological activity is measured by its ability to stimulate the proliferation of human AML5 cells. |
| Biochem/physiol Actions: | Flt-3/Flk-2 Ligand (FL, or Flt-3L) is a transmembrane glycoprotein that binds and activates the Flt-3 receptor. Expression of Flt-3 is primarily restricted among hematopoietic cells to the most primitive progenitor cells. |
| General description: | Mouse and human Flt-3 ligand share ~72% homology and both demonstrate cross-species activity. |
| Physical form: | Lyophilized, 0.2 μm sterile filtered, with with 0.5x PBS. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (SDS-PAGE and HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |