7-Fluorobenzofurazan-4-sulfonic acid ammonium salt

SIGMA/F4383 - ≥98%

Synonym: 4-Fluoro-7-sulfobenzofurazan ammonium salt; 7-Fluorobenz-2,1,3-oxadiazole-4-sulfonic acid ammonium salt; Ammonium 7-fluorobenzofurazan-4-sulfonate; SBD-F

CAS Number: 84806-27-9
Empirical Formula (Hill Notation): C₆H₆FN₃O₄S
Molecular Weight: 235.19
MDL Number: MFCD02682109
Linear Formula: C₆H₃FN₂O₄S · NH₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-F4383-10MG	10 mg	$275.00 1/EA	Add To Favorites
45-F4383-25MG	25 mg	$549.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F4383-10MG

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98%
fluorescence	λ_ex 380 nm; λ_em 515 nm
InChI	1S/C6H3FN2O4S.H3N/c7-3-1-2-4(14(10,11)12)6-5(3)8-13-9-6;/h1-2H,(H,10,11,12);1H3
InChI key	JXLHNMVSKXFWAO-UHFFFAOYSA-N
Quality Level	200
SMILES string	N.OS(=O)(=O)c1ccc(F)c2nonc12
storage condition	protect from light
storage temp.	−20°C

Application:	Fluorescent probe for thiols and pre-column labeling of biological thiols for HPLC
Application:	SBD-F is suitable for the HPLC determination of biological thiols at the picomole level. SBD-F has been used in HPLC methods for measuring total plasma and serum homocysteine levels. It is also suitable to determine metallothionein in a tandem column HPLC method with an isocratic solvent system. SBD-F has been used for determining the position of disulfide linkages of cysteine residues in proteins and for detecting cysteine-containing peptides.
General description:	7-Fluorobenzofurazan-4-sulfonic acid ammonium salt, also known as SBD-F, is a low molecular weight sensitive fluorescent probe. SBD-F reacts with sulfhydryl groups (disulfides do not react with SBD-F and must first be reduced to thiols, such as tributylphosphine) to produce highly fluorescent compounds. The rate of reaction of thiols with SBD-F gradually increases with increasing pH. High fluorescence intensities are observed at pH 2-12. SBD-F has an excitation range between 380-385nm and an emission range between 510-515nm.
Packaging:	1, 10, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
Storage Temp.	−20°C
UNSPSC	12352106

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