Flavin-Containing Monooxygenase-1, Microsomes human
SIGMA/F4928 - recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution
Synonym: FMO-1
Product Type: Chemical
Flavin Containing Monooxygenase is a broad spectrum monooxygenase. Substrates include primary, secondary and tertiary amines, hydrazines, phosphines, boron, sulfide, selenide, and iodide containing compounds.
| form | buffered aqueous solution |
| mol wt | 55-60 kDa |
| packaging | vial of 2.5 mg |
| Quality Level | 200  |
| recombinant | expressed in baculovirus infected insect cells |
| shipped in | dry ice |
| specific activity | See COA for Value |
| storage temp. | −70°C |
| UniProt accession no. | Q01740  |
| Biochem/physiol Actions: | The FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens which contain a nucleophilic nitrogen, sulfur, selenium, or phosphorus-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. |
| Other Notes: | One unit will catalyze the production of 1.0 picomole of methyl p-tolylsulfoxide from methyl p-tolyl sulfide per minute at pH 9.5 at 37 deg C. |
| Physical form: | Solution in 100 mM potassium phosphate buffer, pH 7.4. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: See COA for Value |
| Storage Temp. | −70°C |
| Enzyme Commission (EC) Number | 1.14.13.8 ( BRENDA | IUBMB ) |
| UNSPSC | 12352204 |