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2-Fluoro-2-deoxy-D-glucose

SIGMA/F5006 - glycosylation inhibitor, glucose analog

Synonym: 2-Deoxy-2-fluoro-D-glucose; FDG; 2-Deoxy-2-fluoro-D-glucose; FDG

CAS Number: 29702-43-0
Empirical Formula (Hill Notation): C6H11FO5
Molecular Weight: 182.15
MDL Number: MFCD00077527
Linear Formula: C6H11FO5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F5006-25MG 25 mg
 $373.00
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45-F5006-100MG 100 mg
 $1060.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F5006-100MG

 

assay ≥98.00% (TLC)
color , white to white with yellow cast
concentration ≤100% (2-Fluoro-2-deoxy-D-glucose)
form powder
InChI 1S/C6H11FO5/c7-3-5(10)4(9)2(1-8)12-6(3)11/h2-6,8-11H,1H2
InChI key ZCXUVYAZINUVJD-UHFFFAOYSA-N
mol wt 182.15 g/mol
mp 174-176 °C
Quality Level 300 
SMILES string OCC1OC(O)C(F)C(O)C1O
solubility water: 49.00-51.00 mg/mL, clear, colorless to faintly yellow
storage temp. 2-8°C
Application: 2-Fluoro-2-deoxy-D-glucose is used as a tracer for rapid tumor detection. It is used as a glucose analog to study glucose uptake in mice with radiation and burn injuries. Oncology therapy studies use FDG in combination with PET (Positron Emission Topography)
Biochem/physiol Actions: Glucose analog that inhibits cellular glycosylation.
General description: 2-Fluoro-2-deoxy-D-glucose is non-toxic and a structural analog of glucose, significantly inhibiting glycosylation. As a glucose analog, uptake of 2-Fluoro-2-deoxy-D-glucose is rapid in brain and heart cells.

2-Fluoro-2-deoxy-D-glucose can be taken up by cells but does not undergo metabolic glycolysis.
Packaging: 100 mg in glass bottle
Packaging: 25 mg in poly bottle
Purity ≥98.00% (TLC)
mp 174-176 °C
Storage Temp. 2-8°C
UNSPSC 41116107

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